Paula's Choice
Niacinamide 20% TreatmentA serum built around Niacinamide and Vitamin C derivative, for barrier repair and smoothing.
A serum built around Niacinamide and Vitamin C derivative, for barrier repair and hydration.
Brand price
Not recorded · brand's site
Brand price
USD 59.00 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Silicone-free, Pore-clogger-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients


Benefits

Hydrating5
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Dimethicone, Dimethiconol, Glycerin, Squalane
Barrier Repair7
Strengthens and restores the skin's natural barrier.
Avena Sativa Kernel Extract, Dimethicone, Dimethiconol, Glycerin, Isopropyl Myristate, Niacinamide, Squalane
Hydrating6
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Butylene Glycol, Camellia Sinensis Leaf Extract, Glycerin, Panthenol, Propanediol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Allantoin, Boerhavia Diffusa Root Extract, Camellia Japonica Flower Extract, Camellia Sinensis Leaf Extract, Glycerin, Glycyrrhiza Glabra Root Extract, Lecithin, Niacinamide, Panthenol
Reduces Irritation4
Eases discomfort and supports skin resilience.
Allantoin, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Panthenol
Redness Reducing3
Soothes visible redness and calms irritation.

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
May Worsen Keratosis Pilaris1
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Seborrheic Dermatitis2
May feed the yeast involved in seborrheic dermatitis.

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Acetyl Glucosamine (in both products)
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Ascorbyl Glucoside (in both products)
Antioxidant
- Vitamin C
- Vitamin C derivative (stable)
- Antioxidant
- Brightening
- Dark Spots
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion Stabilising
Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Acetyl Glucosamine (in both products)
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Ascorbyl Glucoside (in both products)
Antioxidant
- Vitamin C
- Vitamin C derivative (stable)
- Antioxidant
- Brightening
- Dark Spots
Skin Conditioning
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Acetyl Glucosamine
Skin Conditioning
Acetyl Glucosamine isn't fungal acne safe.
Learn more about Acetyl Glucosamine →Pentylene Glycol
Skin Conditioning, Solvent
1,2-Dihydroxypentane
Learn more about Pentylene Glycol →Ascorbyl Glucoside
Antioxidant
Ascorbyl Glucoside is a vitamin C derivative.
Learn more about Ascorbyl Glucoside →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →
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