Dr.Althea
345 Relief CreamSkinCeuticals
P-TIOX Anti-Wrinkle CreamA face moisturizer built around Niacinamide and Panthenol, for hydration and barrier repair.
A face cream built around Niacinamide and Zinc salt, for barrier repair and smoothing.
Brand price
USD 27.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 150.00 · checked 28 Sept 2026 · brand's site

At a Glance

They come out differently on Oil-free; that row is shaded. Tap any answer to see why.

Key Ingredients

Centella asiatica (Cica)3
Centella asiatica (cica), used to calm irritation.
Centella Asiatica Extract, Centella Asiatica Leaf Water, Madecassoside
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating10
Boosts hydration and relieves dry, tight skin.
Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Hydrolyzed Hyaluronic Acid, Panthenol, Propanediol, Sodium Hyaluronate, Tocopherol
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Caprylic/Capric Triglyceride, Centella Asiatica Extract, Ceramide NP, Dicaprylyl Carbonate, Glycerin, Hydrogenated Polydecene, Niacinamide, Panthenol, Resveratrol, Tocopherol
Reduces Irritation5
Eases discomfort and supports skin resilience.
Beta-Glucan, Centella Asiatica Extract, Centella Asiatica Leaf Water, Madecassoside, Panthenol
Redness Reducing4
Soothes visible redness and calms irritation.
Centella Asiatica Extract, Centella Asiatica Leaf Water, Madecassoside, Niacinamide
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Tocopherol, Zinc PCA
Barrier Repair14
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Dicaprylyl Carbonate, Glycerin, Isododecane, Macadamia Integrifolia Seed Oil, Niacinamide, Palmitic Acid, Tocopherol
Reduces Irritation2
Eases discomfort and supports skin resilience.

Concerns

May Worsen Seborrheic Dermatitis5
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Sodium Stearoyl Glutamate
May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter, C12-16 Alcohols, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Glyceryl Stearate Se, Hydrogenated Lecithin, Macadamia Integrifolia Seed Oil, Palmitic Acid, Palmitoyl Tetrapeptide-10, Polysorbate 80, Sorbitan Stearate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Oily Skin2
May increase shine or excess oil.
Butyrospermum Parkii Butter, Macadamia Integrifolia Seed Oil

Ingredients Side-by-side

Melaleuca Alternifolia Leaf Water
Antimicrobial
1,2-Hexanediol (in both products)
Skin Conditioning
Emollient
C14-22 Alcohols (in both products)
Emulsion Stabilising
- Fatty alcohols (Malassezia)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Dicaprylyl Carbonate (in both products)
Emollient
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
1,2-Hexanediol (in both products)
Skin Conditioning
Emollient
C14-22 Alcohols (in both products)
Emulsion Stabilising
- Fatty alcohols (Malassezia)
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Vinyl Dimethicone
Viscosity Controlling
Vinyl Dimethicone is a silicone.
Learn more about Vinyl Dimethicone →C14-22 Alcohols
Emulsion Stabilising
C14-22 Alcohols isn't fungal acne safe.
Learn more about C14-22 Alcohols →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Dicaprylyl Carbonate
Skin Conditioning, Emollient
Carbonic Acid, Dicaprylyl Ester
Learn more about Dicaprylyl Carbonate →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →C12-20 Alkyl Glucoside
Cleansing, Emulsifying
C12-20 Alkyl Glucoside isn't fungal acne safe.
Learn more about C12-20 Alkyl Glucoside →
Similar Comparisons
Each product against its closest dupes.
- View the comparison

Dr.Althea
345 Relief Cream

Arencia
Eraser Soothing Cream
- View the comparison

SkinCeuticals
P-TIOX Anti-Wrinkle Cream

Arencia
Eraser Soothing Cream
- View the comparison

Dr.Althea
345 Relief Cream

Skin1004
Tea-Trica B5 Cream
- View the comparison

SkinCeuticals
P-TIOX Anti-Wrinkle Cream

Medicube
3H Daily Relief Cream