Dr.Althea
345 Relief SerumA serum built around Niacinamide and Panthenol, for hydration and barrier repair.
A serum built around Niacinamide and Centella asiatica, for soothing irritation and reducing redness.
Brand price
USD 22.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 129.00 · checked 28 Sept 2026 · brand's site
At a Glance
They come out differently on Cruelty-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Centella asiatica (Cica)5
Centella asiatica (cica), used to calm irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Madecassoside
Hyaluronic acid3
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer
Centella asiatica (Cica)5
Centella asiatica (cica), used to calm irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Madecassoside
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Benefits
Hydrating13
Boosts hydration and relieves dry, tight skin.
Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Panthenol, Polyglutamic Acid, Propanediol, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Xylose
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Caprylic/Capric Triglyceride, Caprylyl Glycol, Centella Asiatica Extract, Ceramide NP, Cholesterol, Glycerin, Glyceryl Caprylate, Hydrogenated Polydecene, Niacinamide, Panthenol, Resveratrol
Reduces Irritation7
Eases discomfort and supports skin resilience.
Asiatic Acid, Asiaticoside, Beta-Glucan, Centella Asiatica Extract, Madecassic Acid, Madecassoside, Panthenol
Redness Reducing6
Soothes visible redness and calms irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Madecassoside, Niacinamide
Hydrating5
Boosts hydration and relieves dry, tight skin.
Aloe Barbadensis Leaf Extract, Butylene Glycol, Glycerin, Panthenol, Sodium Hyaluronate
Barrier Repair7
Strengthens and restores the skin's natural barrier.
Aloe Barbadensis Leaf Extract, Centella Asiatica Extract, Fucus Vesiculosus Extract, Glycerin, Hydroxypropyl Bispalmitamide MEA, Niacinamide, Panthenol
Reduces Irritation7
Eases discomfort and supports skin resilience.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Fucus Vesiculosus Extract, Madecassic Acid, Madecassoside, Panthenol
Redness Reducing7
Soothes visible redness and calms irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Fucus Vesiculosus Extract, Madecassic Acid, Madecassoside, Niacinamide
Concerns
May Worsen Seborrheic Dermatitis8
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aluminum/Magnesium Hydroxide Stearate, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Hydrogenated Lecithin, Lysolecithin, Phosphatidylcholine
May Worsen Seborrheic Dermatitis1
May feed the yeast involved in seborrheic dermatitis.
Ingredients Side-by-side
Betula Platyphylla Japonica Juice
Skin Conditioning
Melaleuca Alternifolia Leaf Water
Antimicrobial
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Panthenol (in both products)
Skin Conditioning
0 / 0
- Panthenol (provitamin B5)
- Barrier Repair
- Hydrating
- Reduces Irritation
1,2-Hexanediol (in both products)
Skin Conditioning
Skin Conditioning
1,2-Hexanediol (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Centella Asiatica Extract (in both products)
Cleansing
- Centella asiatica (Cica)
- Barrier Repair
- Redness Reducing
- Reduces Irritation
Panthenol (in both products)
Skin Conditioning
0 / 0
- Panthenol (provitamin B5)
- Barrier Repair
- Hydrating
- Reduces Irritation
Skin Conditioning
Madecassic Acid (in both products)
Skin Conditioning
- Centella asiatica (Cica)
- Redness Reducing
- Reduces Irritation
Asiaticoside (in both products)
Antioxidant
- Centella asiatica (Cica)
- Redness Reducing
- Reduces Irritation
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Panthenol
Antistatic, Hair Conditioning, Skin Conditioning
Panthenol is panthenol (provitamin B5).
Learn more about Panthenol →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Disodium EDTA
Chelating, Viscosity Controlling
Disodium dihydrogen ethylenediaminetetraacetate
Learn more about Disodium EDTA →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Madecassoside
Antioxidant, Skin Conditioning
Madecassoside is centella (cica).
Learn more about Madecassoside →Asiaticoside
Antioxidant, Perfuming, Skin Conditioning
Asiaticoside is centella (cica).
Learn more about Asiaticoside →Asiatic Acid
Light Stabilizer, Skin Conditioning
Asiatic Acid is centella (cica).
Learn more about Asiatic Acid →
Similar Comparisons
Each product against its closest dupes.
- View the comparison
Dr.Althea
345 Relief Serum
Skin1004
Probio-Cica Intensive Ampoule
- View the comparison
Rejuran
Recover c-PDRN® Lifting Ampoule
Purito
Wonder Releaf Centella Serum Unscented
- View the comparison
Dr.Althea
345 Relief Serum
COSRX
5 PDRN Collagen Intense Vitalizing Serum
- View the comparison
Rejuran
Recover c-PDRN® Lifting Ampoule
Purito
Wonder Releaf Centella Serum