Medicube
Zero Pore One-day Peptide SerumA serum built around Niacinamide and Vitamin E, for barrier repair and smoothing.
A serum built around PHA and Niacinamide, for hydration and smoothing.
Brand price
USD 37.00 · checked 8 Oct 2026 · brand's site
Brand price
USD 26.00 · checked 26 Sept 2026 · brand's site

At a Glance

They come out differently on Pore-clogger-free, Oil-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Centella asiatica (Cica)2
Centella asiatica (cica), used to calm irritation.

Benefits

Hydrating12
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Camellia Sinensis Leaf Extract, Dipotassium Glycyrrhizate, Glycerin, Helianthus Annuus Seed Oil, Hyaluronic Acid, Hydroxyethyl Urea, Propanediol, Sodium Hyaluronate, Squalane, Stearic Acid, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Allantoin, Camellia Sinensis Leaf Extract, Cetearyl Alcohol, Glycerin, Glyceryl Stearate, Glycine Soja Oil, Helianthus Annuus Seed Oil, Niacinamide, Palmitic Acid, Sodium Polyacrylate, Squalane, Stearic Acid, Tocopherol
Reduces Irritation4
Eases discomfort and supports skin resilience.
Achillea Millefolium Extract, Allantoin, Camellia Sinensis Leaf Extract, Dipotassium Glycyrrhizate
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating12
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Gluconolactone, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Lactic Acid, Polyglycerin-3, Propanediol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Allantoin, Centella Asiatica Extract, Dimethicone, Glycerin, Lecithin, Niacinamide
Reduces Irritation3
Eases discomfort and supports skin resilience.
Redness Reducing4
Soothes visible redness and calms irritation.
Allantoin, Centella Asiatica Extract, Madecassoside, Niacinamide

Concerns

May Trigger Acne7
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glycine Soja Oil, Lauric Acid, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol
May Worsen Seborrheic Dermatitis11
May feed the yeast involved in seborrheic dermatitis.
Cetearyl Alcohol, Glyceryl Stearate, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydrogenated Lecithin, Lauric Acid, Myristic Acid, Palmitic Acid, Polyglyceryl-3 Methylglucose Distearate, Sodium Stearoyl Glutamate, Stearic Acid
May Worsen Keratosis Pilaris7
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glycine Soja Oil, Lauric Acid, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol
May Worsen Oily Skin3
May increase shine or excess oil.
May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.

Ingredients Side-by-side

Lactobacillus Ferment Lysate (in both products)
Skin Conditioning
Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Viscosity Controlling
Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Lactobacillus Ferment Lysate
Skin Conditioning
Lactobacillus Ferment Lysate is a lysate of the product obtained by fermentation of Lactobacillus.
Learn more about Lactobacillus Ferment Lysate →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Propanediol
Solvent, Viscosity Controlling
Propanediol is the organic compound that conforms to the formula
Learn more about Propanediol →Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Ammonium Acryloyldimethyltaurate/Vp Copolymer
Viscosity Controlling
Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers
Learn more about Ammonium Acryloyldimethyltaurate/Vp Copolymer →Allantoin
Skin Conditioning, Skin Protecting, Soothing
Urea, (2,5-dioxo-4-imidazolidinyl)-
Learn more about Allantoin →Pentylene Glycol
Skin Conditioning, Solvent
1,2-Dihydroxypentane
Learn more about Pentylene Glycol →
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