La Roche-Posay
Effaclar Salicylic Acid Acne Treatment SerumPaula's Choice
1% Retinol BoosterA serum built around AHA and Glycolic acid, for smoothing and brightening.
A serum built around Retinoid and Ceramide, for barrier repair and hydration.
Brand price
USD 44.99 · checked 25 Sept 2026 · brand's site
Brand price
USD 55.00 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, Alcohol-free, Oil-free, Vegan and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients


Benefits

Hydrating5
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Ceramide NP, Dipotassium Glycyrrhizate, Glycerin, Glyceryl Ascorbate
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Allantoin, Avena Sativa Kernel Extract, Caprylyl Glycol, Carthamus Tinctorius Seed Oil, Ceramide NP, Glycerin
Reduces Irritation3
Eases discomfort and supports skin resilience.
Allantoin, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
PEG-30 Glyceryl Cocoate, PEG-40 Hydrogenated Castor Oil, PEG-60 Hydrogenated Castor Oil
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Carthamus Tinctorius Seed Oil, Ceramide NP, Ethylhexyl Olivate, Hydrogenated Lecithin, Palmitoyl Tripeptide-1, Polyglyceryl-10 Laurate, Polysorbate 20

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
Water (in both products)
Skin Conditioning
Skin Conditioning
0 / 0
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Polyglyceryl-10 Caprylate/Caprate
Cleansing
Skin Conditioning
Cleansing
0 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Polysorbates (Tween emulsifiers)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Retinoid
- Acne Fighting
- Anti-Aging
- Dark Spots
- Firming
- Oil Control
- Pore Refining
- Smoothing
Glycyrrhiza Glabra
Skin Conditioning
- Ceramide
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Barrier Repair
- Hydrating
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →
Similar Comparisons
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La Roche-Posay
Effaclar Salicylic Acid Acne Treatment Serum

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Blemish + Age Defense Serum
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1% Retinol Booster

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1% Retinol Treatment
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La Roche-Posay
Effaclar Salicylic Acid Acne Treatment Serum

The Derma Co
Sali-Cinamide Anti-Acne Serum with 2% Salicylic Acid & 5% Niacinamide
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Paula's Choice
1% Retinol Booster

Isntree
Hyper Retinol EX 1.0 Serum