La Roche-Posay Vitamin C12 Serum vs The Derma Co 0.3% Retinol Serum

La Roche-Posay

The Derma Co

A serum built around Vitamin C and Vitamin C, for barrier repair and hydration.

A serum built around Vitamin C derivative and Vitamin C, for barrier repair and smoothing.

Serum

29 ingredients

27 ingredients

Brand price

USD 44.99 · checked 25 Sept 2026 · brand's site

Brand price

INR 799.00 · checked 5 Oct 2026 · brand's site

No retailer listed yet

Brand from France

Brand from India

At a Glance

They come out differently on Fragrance-free, Alcohol-free and Pore-clogger-free; those rows are shaded. Tap any answer to see why.

Vitamin E1
Tocopherols — fat-soluble antioxidants.
Tocopherol
Vitamin C (L-ascorbic acid)1
L-ascorbic acid, the unesterified form of vitamin C.
Ascorbic Acid
BHA1
Beta hydroxy acid — oil-soluble, so it works inside the pore.
Salicylic Acid
Salicylic acid1
The BHA used in acne treatment.
Salicylic Acid

Vitamin C derivative (stable)1
Stable derivatives of ascorbic acid.
Tetrahexyldecyl Ascorbate
Polysorbates (Tween emulsifiers)1
Polysorbate (Tween) emulsifiers.
Polysorbate 20
Retinoid1
Vitamin A derivatives that speed cell turnover.
Retinol
Vitamin C1
Vitamin C in any form: an antioxidant and brightener.
Tetrahexyldecyl Ascorbate

Hydrating6
Boosts hydration and relieves dry, tight skin.
Dimethicone, Glycerin, Hydrolyzed Hyaluronic Acid, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair8
Strengthens and restores the skin's natural barrier.
C13-14 Isoparaffin, Caprylyl Glycol, Cyclohexasiloxane, Dimethicone, Glycerin, Pentaerythrityl Tetraethylhexanoate, Propylene Glycol, Tocopherol
Anti-Aging2
Softens lines and helps skin look youthful.
Adenosine, Ascorbic Acid
Firming1
Supports elasticity and bounce.
Adenosine

May Trigger Acne1
Can clog pores or trigger breakouts.
Tocopherol
May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Acetyl Dipeptide-1 Cetyl Ester, Laureth-7, PEG-20 Methyl Glucose Sesquistearate
May Worsen Keratosis Pilaris1
May clog follicles or strip skin prone to keratosis pilaris.
Tocopherol
May Worsen Irritation3
May cause stinging, redness or sensitivity.
Alcohol Denat., Parfum, Tocopherol

Show highlights for:

Aqua (in both products)
Solvent
0 / —
Ascorbic Acid
Antioxidant
- Vitamin C
- Vitamin C (L-ascorbic acid)
- Anti-Aging
- Anti-Pollution
- Antioxidant
- Brightening
- Dark Spots
- Even Tone
Cyclohexasiloxane
Emollient
0-1 / —
- Silicones
Glycerin (in both products)
Humectant
0 / 0
- Possibly animal-derived
- Hydrating
Alcohol Denat.
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Potassium Hydroxide
Buffering
0-1 / —
Polymethylsilsesquioxane
Opacifying
0-1 / —
- Silicones
Polysilicone-11
Film Forming
- Silicones
Dimethicone
Emollient
1 / 0
- Silicones
- Barrier Repair
- Hydrating
- Smoothing
Propylene Glycol
Humectant
0 / 0

Aqua (in both products)
Solvent
0 / —
Ethylhexyl Methoxycrylene
Skin Conditioning
Diethylhexyl Carbonate
Emollient
Ethoxydiglycol
Humectant
0 / 0
Glycerin (in both products)
Humectant
0 / 0
- Possibly animal-derived
- Hydrating
Tetrahexyldecyl Ascorbate
Antioxidant
- Fatty alcohols (Malassezia)
- Vitamin C
- Vitamin C derivative (stable)
- Antioxidant
- Brightening
- Dark Spots
- May Worsen Seborrheic Dermatitis
Dimethylmethoxy Chromanol
Antioxidant
Physalis Angulata Extract
Skin Protecting
Caprylic/Capric Triglyceride
Occlusive
1 / 1
Cyclopentasiloxane
Emollient
0-1 / —
- Silicones

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Aqua
Solvent
Water
Learn more about Aqua →
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →
BHT
Antioxidant, Fragrance
BHT is a substituted toluene that conforms to the formula:
Learn more about BHT →