Medicube
PDRN Pink Collagen Exosome ShotPaula's Choice
1% Retinol TreatmentA serum built around Niacinamide and Panthenol, for barrier repair and hydration.
A serum built around Vitamin C derivative and Vitamin C, for barrier repair and smoothing.
Brand price
USD 24.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 48.75 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Alcohol-free, Oil-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients


Benefits

Hydrating12
Boosts hydration and relieves dry, tight skin.
Acetyl Tetrapeptide-5, Butylene Glycol, Caprylic/Capric Triglyceride, Glycerin, Glyceryl Acrylate/Acrylic Acid Copolymer, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Panthenol, Phenyl Trimethicone, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Brassica Campestris Sterols, Caprylic/Capric Triglyceride, Caprylyl Glycol, Cetearyl Olivate, Cholesterol, Glycerin, Hydrolyzed Elastin, Macadamia Ternifolia Seed Oil, Milk Exosomes, Niacinamide, Panthenol, Phenyl Trimethicone, Sodium Polyacrylate
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Hydrolyzed Soy Protein, PEG-14, PEG-33, Sodium Hyaluronate
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Allantoin, Arachidyl Alcohol, Avena Sativa Kernel Extract, Behenyl Alcohol, C12-15 Alkyl Benzoate, Caprylyl Glycol, Dimethicone, Glycerin, Glyceryl Stearate, Glycine Soja Sterols, Glycyrrhiza Glabra Root Extract, Isononyl Isononanoate, Lecithin, Pentaerythrityl Tetraisostearate, PPG-12/SMDI Copolymer, Tribehenin
Reduces Irritation5
Eases discomfort and supports skin resilience.
Allantoin, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Palmitoyl Tetrapeptide-7
Redness Reducing2
Soothes visible redness and calms irritation.

Concerns

May Worsen Seborrheic Dermatitis12
May feed the yeast involved in seborrheic dermatitis.
Cetearyl Olivate, Ceteth-3, Ceteth-5, Hydrogenated Lecithin, Macadamia Ternifolia Seed Oil, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5, Polyglyceryl-10 Laurate, Polysorbate 20, Potassium Cetyl Phosphate, Sodium Acetylated Hyaluronate, Sorbitan Olivate
May Trigger Acne2
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Acetyl Dipeptide-1 Cetyl Ester, Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, C12-15 Alkyl Benzoate, Castor Isostearate Succinate, Ceramide Ng, Glyceryl Stearate, Lecithin, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, PEG-100 Stearate, PEG-75 Shea Butter Glycerides, Pentaerythrityl Tetraisostearate, Polysorbate 20, Sorbitan Laurate, Tetrahexyldecyl Ascorbate, Tribehenin
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
Skin Conditioning
Water (in both products)
Skin Conditioning
Emollient
Skin Conditioning
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Humectant
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Disodium EDTA
Chelating, Viscosity Controlling
Disodium dihydrogen ethylenediaminetetraacetate
Learn more about Disodium EDTA →Polysorbate 20
Cleansing, Emulsifying
Polysorbate 20 isn't fungal acne safe.
Learn more about Polysorbate 20 →Retinol
Skin Conditioning
Retinol is a retinoid.
Learn more about Retinol →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Tocopheryl Acetate
Antioxidant, Skin Conditioning
Tocopheryl Acetate is vitamin E.
Learn more about Tocopheryl Acetate →
Similar Comparisons
Each product against its closest dupes.
- View the comparison

Medicube
PDRN Pink Collagen Exosome Shot

Medicube
Azelaic Acid Exosome Shot
- View the comparison

Paula's Choice
1% Retinol Treatment

Paula's Choice
1% Retinol Booster
- View the comparison

Medicube
PDRN Pink Collagen Exosome Shot

Biodance
Pore Perfecting Collagen Peptide Serum
- View the comparison

Paula's Choice
1% Retinol Treatment

No7
Pure Retinol 1% Night Concentrate