Medicube
Retinol NMN Boosting SerumSkintific
377 Dark Spot SerumA serum built around Retinoid and Vitamin E, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for hydration and barrier repair.
Brand price
USD 26.00 · checked 26 Sept 2026 · brand's site
Brand price
AUD 34.90 · checked 5 Oct 2026 · brand's site

At a Glance

They come out differently on Reef-safe and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Chemical sunscreen2
Organic UV filters that absorb UV and release it as heat.
Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Methoxycinnamate
Sunscreen2
Any ingredient acting as a UV filter.
Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Methoxycinnamate

Benefits

Hydrating13
Boosts hydration and relieves dry, tight skin.
Acetyl Hexapeptide-8, Acetyl Tetrapeptide-5, Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Glycereth-26, Glycerin, Panthenol, Propanediol, Sodium Hyaluronate Crosspolymer, Squalane, Tocopherol
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Allantoin, Bifida Ferment Lysate, Brassica Campestris Sterols, Camellia Japonica Flower Extract, Caprylic/Capric Triglyceride, Ceramide NP, Cetyl Ethylhexanoate, Cholesterol, Elaeis Guineensis Oil, Eriobotrya Japonica Leaf Extract, Glycerin, Macadamia Ternifolia Seed Oil, Niacinamide, Panthenol, Squalane, Tocopherol
Reduces Irritation8
Eases discomfort and supports skin resilience.
Allantoin, Asiatic Acid, Asiaticoside, Beta-Glucan, Centella Asiatica Leaf Extract, Madecassic Acid, Palmitoyl Tetrapeptide-7, Panthenol
Redness Reducing6
Soothes visible redness and calms irritation.
Allantoin, Asiatic Acid, Asiaticoside, Centella Asiatica Leaf Extract, Madecassic Acid, Niacinamide
Hydrating15
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Ectoin, Fructose, Glycereth-26, Glycerin, Maris Aqua, Pancratium Maritimum Extract, Simmondsia Chinensis Seed Oil, Sodium Hyaluronate, Squalane, Tocopherol
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Allantoin, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Lecithin, Niacinamide, Pancratium Maritimum Extract, Simmondsia Chinensis Seed Oil, Squalane, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Acetyl Hexapeptide-8, Aluminum/Magnesium Hydroxide Stearate, Ceramide NP, Cetyl Ethylhexanoate, Elaeis Guineensis Oil, Glyceryl Citrate/Lactate/Linoleate/Oleate, Hydrogenated Lecithin, Macadamia Ternifolia Seed Oil, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Polyacrylate Crosspolymer-6, Polyglyceryl-10 Laurate, Polyglyceryl-10 Oleate, Potassium Cetyl Phosphate
May Worsen Oily Skin3
May increase shine or excess oil.
Elaeis Guineensis Oil, Macadamia Ternifolia Seed Oil, Squalane
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
Acetyl Glucosamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ceramide NP, Hydrogenated Lecithin, Lecithin, Phosphatidylcholine, Polysorbate 80, Simmondsia Chinensis Seed Oil, Sodium Stearoyl Glutamate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Water (in both products)
Skin Conditioning
Emollient
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Hydrogenated Lecithin (in both products)
Emulsifying
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Hydroxyacetophenone (in both products)
Antioxidant
1,2-Hexanediol (in both products)
Skin Conditioning
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Glycereth-26
Humectant, Viscosity Controlling
Poly(oxy-1,2-ethanediyl)], .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxy-
Learn more about Glycereth-26 →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Hydroxyacetophenone
Antioxidant
Hydroxyacetophenone is the organic compound
Learn more about Hydroxyacetophenone →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →
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