Medicube
Zero Pore One-day Peptide SerumA serum built around PHA and Niacinamide, for hydration and smoothing.
A serum built around Niacinamide and Hyaluronic acid, for hydration and barrier repair.
Brand price
USD 26.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 22.00 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Silicone-free and Pore-clogger-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Centella asiatica (Cica)2
Centella asiatica (cica), used to calm irritation.
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.

Benefits

Hydrating12
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Gluconolactone, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Lactic Acid, Polyglycerin-3, Propanediol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Allantoin, Centella Asiatica Extract, Dimethicone, Glycerin, Lecithin, Niacinamide
Reduces Irritation3
Eases discomfort and supports skin resilience.
Redness Reducing4
Soothes visible redness and calms irritation.
Allantoin, Centella Asiatica Extract, Madecassoside, Niacinamide
Hydrating16
Boosts hydration and relieves dry, tight skin.
Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Collagen, Collagen Water, Glycereth-26, Glycerin, Hydrolyzed Collagen, Polyglutamic Acid, Polyglycerin-3, Propanediol, Sodium Hyaluronate, Soluble Collagen, Squalane, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Olivate, Glycerin, Hydrolyzed Collagen, Niacinamide, Panax Ginseng Root Extract, Squalane, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
May Worsen Seborrheic Dermatitis5
May feed the yeast involved in seborrheic dermatitis.
Ceramide NP, Cetearyl Olivate, Hydrogenated Lecithin, Polyglyceryl-10 Laurate, Sorbitan Olivate

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Water (in both products)
Skin Conditioning
1,2-Hexanediol (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Methylpropanediol
Solvent
2-Methyl-1,3-propanediol
Learn more about Methylpropanediol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Propanediol
Solvent, Viscosity Controlling
Propanediol is the organic compound that conforms to the formula
Learn more about Propanediol →Tromethamine
Buffering, Fragrance
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about Tromethamine →Polyglycerin-3
Humectant
Triglycerol
Learn more about Polyglycerin-3 →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Ammonium Acryloyldimethyltaurate/Vp Copolymer
Viscosity Controlling
Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers
Learn more about Ammonium Acryloyldimethyltaurate/Vp Copolymer →
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