Medicube
Zero Pore One-day Peptide SerumPaula's Choice
1% Retinol TreatmentA serum built around PHA and Niacinamide, for hydration and smoothing.
A serum built around Vitamin C derivative and Vitamin C, for barrier repair and smoothing.
Brand price
USD 26.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 48.75 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Cruelty-free; that row is shaded. Tap any answer to see why.

Key Ingredients

Centella asiatica (Cica)2
Centella asiatica (cica), used to calm irritation.

Benefits

Hydrating12
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Gluconolactone, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Lactic Acid, Polyglycerin-3, Propanediol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Allantoin, Centella Asiatica Extract, Dimethicone, Glycerin, Lecithin, Niacinamide
Reduces Irritation3
Eases discomfort and supports skin resilience.
Redness Reducing4
Soothes visible redness and calms irritation.
Allantoin, Centella Asiatica Extract, Madecassoside, Niacinamide
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Hydrolyzed Soy Protein, PEG-14, PEG-33, Sodium Hyaluronate
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Allantoin, Arachidyl Alcohol, Avena Sativa Kernel Extract, Behenyl Alcohol, C12-15 Alkyl Benzoate, Caprylyl Glycol, Dimethicone, Glycerin, Glyceryl Stearate, Glycine Soja Sterols, Glycyrrhiza Glabra Root Extract, Isononyl Isononanoate, Lecithin, Pentaerythrityl Tetraisostearate, PPG-12/SMDI Copolymer, Tribehenin
Reduces Irritation5
Eases discomfort and supports skin resilience.
Allantoin, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Palmitoyl Tetrapeptide-7
Redness Reducing2
Soothes visible redness and calms irritation.

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
May Trigger Acne2
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Acetyl Dipeptide-1 Cetyl Ester, Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, C12-15 Alkyl Benzoate, Castor Isostearate Succinate, Ceramide Ng, Glyceryl Stearate, Lecithin, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, PEG-100 Stearate, PEG-75 Shea Butter Glycerides, Pentaerythrityl Tetraisostearate, Polysorbate 20, Sorbitan Laurate, Tetrahexyldecyl Ascorbate, Tribehenin
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
Water (in both products)
Skin Conditioning
Emollient
Skin Conditioning
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Humectant
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Hydroxyethylcellulose
Binding, Emulsion Stabilising, Film Forming, Light Stabilizer, Viscosity Controlling
Cellulose, 2-hydroxyethyl ether
Learn more about Hydroxyethylcellulose →Lecithin
Antistatic, Skin Conditioning, Emollient, Emulsifying
Lecithin isn't fungal acne safe.
Learn more about Lecithin →Allantoin
Skin Conditioning, Skin Protecting, Soothing
Urea, (2,5-dioxo-4-imidazolidinyl)-
Learn more about Allantoin →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Pentylene Glycol
Skin Conditioning, Solvent
1,2-Dihydroxypentane
Learn more about Pentylene Glycol →
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