Medicube
Zero Pore One-day Peptide SerumA serum built around PHA and Niacinamide, for hydration and smoothing.
A serum built around Niacinamide and BHA, for hydration and barrier repair.
Brand price
USD 26.00 · checked 26 Sept 2026 · brand's site
Brand price
AUD 21.90 · checked 5 Oct 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, EU-allergen-free, Silicone-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Centella asiatica (Cica)2
Centella asiatica (cica), used to calm irritation.
Centella asiatica (Cica)1
Centella asiatica (cica), used to calm irritation.

Benefits

Hydrating12
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Gluconolactone, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Lactic Acid, Polyglycerin-3, Propanediol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Allantoin, Centella Asiatica Extract, Dimethicone, Glycerin, Lecithin, Niacinamide
Reduces Irritation3
Eases discomfort and supports skin resilience.
Redness Reducing4
Soothes visible redness and calms irritation.
Allantoin, Centella Asiatica Extract, Madecassoside, Niacinamide
Hydrating11
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Ceramide AP, Ceramide NP, Dipotassium Glycyrrhizate, Ectoin, Glycerin, Propanediol, Sodium Hyaluronate, Sodium Lactate, Sucrose, Urea
Barrier Repair8
Strengthens and restores the skin's natural barrier.
Allantoin, Caprylyl Glycol, Centella Asiatica Extract, Ceramide AP, Ceramide NP, Glycerin, Glyceryl Caprylate, Niacinamide
Reduces Irritation5
Eases discomfort and supports skin resilience.
Allantoin, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Menthol, Sucrose
Redness Reducing5
Soothes visible redness and calms irritation.
Allantoin, Centella Asiatica Extract, Menthol, Niacinamide, Sucrose

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ceramide AP, Ceramide NP, Ceramide Ns, Glycolipids, Glycosphingolipids, PEG-40 Hydrogenated Castor Oil
May Worsen Keratosis Pilaris1
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
1,2-Hexanediol (in both products)
Skin Conditioning
Salicylic Acid (in both products)
Preservative
- BHA
- Salicylic acid
- Acne Fighting
- Exfoliating
- Oil Control
- Pore Refining
Fragrance
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion Stabilising
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Methylpropanediol
Solvent
2-Methyl-1,3-propanediol
Learn more about Methylpropanediol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Propanediol
Solvent, Viscosity Controlling
Propanediol is the organic compound that conforms to the formula
Learn more about Propanediol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Salicylic Acid
Anti-seborrheic, Fragrance, Hair Conditioning, Keratolytic, Preservative, Skin Conditioning
Salicylic Acid is a BHA.
Learn more about Salicylic Acid →Allantoin
Skin Conditioning, Skin Protecting, Soothing
Urea, (2,5-dioxo-4-imidazolidinyl)-
Learn more about Allantoin →Glycolic Acid
Buffering
Glycolic Acid is an AHA.
Learn more about Glycolic Acid →
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