Medik8
C-Tetra® AdvancedPaula's Choice
1% Retinol TreatmentA serum built around Vitamin C derivative and Vitamin C, for barrier repair and hydration.
A serum built around Vitamin C derivative and Vitamin C, for barrier repair and smoothing.
Brand price
GBP 72.00 · checked 8 Oct 2026 · brand's site
Brand price
USD 48.75 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, EU-allergen-free, Silicone-free and Pore-clogger-free; those rows are shaded. Tap any answer to see why.

Key Ingredients


Benefits

Hydrating6
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Glycerin, Propanediol, Sodium Hyaluronate, Squalane, Tocopherol
Barrier Repair7
Strengthens and restores the skin's natural barrier.
Acetyl Zingerone, Avena Sativa Kernel Extract, Glycerin, Isododecane, Squalane, Sucrose Stearate, Tocopherol
Smoothing5
Refines rough or uneven texture.
Avena Sativa Kernel Extract, Citric Acid, Isododecane, Squalane, Sucrose Stearate
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Hydrolyzed Soy Protein, PEG-14, PEG-33, Sodium Hyaluronate
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Allantoin, Arachidyl Alcohol, Avena Sativa Kernel Extract, Behenyl Alcohol, C12-15 Alkyl Benzoate, Caprylyl Glycol, Dimethicone, Glycerin, Glyceryl Stearate, Glycine Soja Sterols, Glycyrrhiza Glabra Root Extract, Isononyl Isononanoate, Lecithin, Pentaerythrityl Tetraisostearate, PPG-12/SMDI Copolymer, Tribehenin
Reduces Irritation5
Eases discomfort and supports skin resilience.
Allantoin, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Palmitoyl Tetrapeptide-7
Redness Reducing2
Soothes visible redness and calms irritation.

Concerns

May Worsen Seborrheic Dermatitis6
May feed the yeast involved in seborrheic dermatitis.
Acetyl Glucosamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 60, Sorbitan Isostearate, Sucrose Stearate, Tetrahexyldecyl Ascorbate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Trigger Acne2
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Acetyl Dipeptide-1 Cetyl Ester, Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, C12-15 Alkyl Benzoate, Castor Isostearate Succinate, Ceramide Ng, Glyceryl Stearate, Lecithin, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, PEG-100 Stearate, PEG-75 Shea Butter Glycerides, Pentaerythrityl Tetraisostearate, Polysorbate 20, Sorbitan Laurate, Tetrahexyldecyl Ascorbate, Tribehenin
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Tetrahexyldecyl Ascorbate (in both products)
Antioxidant
- Fatty alcohols (Malassezia)
- Vitamin C
- Vitamin C derivative (stable)
- Antioxidant
- Brightening
- Dark Spots
- May Worsen Seborrheic Dermatitis
Emollient
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Occlusive
0-3 / 3
- Vitamin E
- Anti-Pollution
- Antioxidant
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
Antioxidant
Camellia Sinensis Leaf Vesicles
Skin Conditioning
Antioxidant
Skin Conditioning
Emollient
Skin Conditioning
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Humectant
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Tetrahexyldecyl Ascorbate
Antioxidant, Skin Conditioning
Tetrahexyldecyl Ascorbate isn't fungal acne safe.
Learn more about Tetrahexyldecyl Ascorbate →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Avena Sativa Kernel Extract
Abrasive, Antioxidant, Skin Conditioning, Emollient
Avena Sativa Kernel Extract is colloidal oatmeal.
Learn more about Avena Sativa Kernel Extract →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →
Similar Comparisons
Each product against its closest dupes.
- View the comparison

Medik8
C-Tetra® Advanced

Medik8
Niacinamide Peptides
- View the comparison

Paula's Choice
1% Retinol Treatment

Paula's Choice
1% Retinol Booster
- View the comparison

Paula's Choice
1% Retinol Treatment

No7
Pure Retinol 1% Night Concentrate
- View the comparison

Paula's Choice
1% Retinol Treatment

No7
Pure Retinol 0.3% Retinol Night Concentrate