Paula's Choice
Niacinamide 20% TreatmentIsntree
Onion Newpair Ampoule PlusA serum built around Niacinamide and Vitamin C derivative, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for hydration and barrier repair.
Brand price
USD 59.00 · checked 8 Oct 2026 · brand's site
Brand price
Not recorded · brand's site
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At a Glance
Every check both products could be assessed on comes out the same. Tap any answer to see why.
Key Ingredients
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Benefits
Hydrating6
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Butylene Glycol, Camellia Sinensis Leaf Extract, Glycerin, Panthenol, Propanediol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Allantoin, Boerhavia Diffusa Root Extract, Camellia Japonica Flower Extract, Camellia Sinensis Leaf Extract, Glycerin, Glycyrrhiza Glabra Root Extract, Lecithin, Niacinamide, Panthenol
Reduces Irritation4
Eases discomfort and supports skin resilience.
Allantoin, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Panthenol
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating11
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Betaine, Butylene Glycol, Glycerin, Hydrolyzed Hyaluronic Acid, Panthenol, Propanediol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Squalane, Trehalose
Barrier Repair7
Strengthens and restores the skin's natural barrier.
Allantoin, Betaine, Caprylyl Glycol, Glycerin, Niacinamide, Panthenol, Squalane
Redness Reducing3
Soothes visible redness and calms irritation.
Concerns
May Worsen Seborrheic Dermatitis2
May feed the yeast involved in seborrheic dermatitis.
May Worsen Seborrheic Dermatitis5
May feed the yeast involved in seborrheic dermatitis.
Acetyl Glucosamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydrogenated Lecithin, Polyglyceryl-10 Laurate, Sodium Acetylated Hyaluronate
Ingredients Side-by-side
Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Acetyl Glucosamine (in both products)
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Skin Conditioning
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Water (in both products)
Skin Conditioning
Antioxidant
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Pentylene Glycol
Skin Conditioning, Solvent
1,2-Dihydroxypentane
Learn more about Pentylene Glycol →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Acetyl Glucosamine
Skin Conditioning
Acetyl Glucosamine isn't fungal acne safe.
Learn more about Acetyl Glucosamine →Allantoin
Skin Conditioning, Skin Protecting, Soothing
Urea, (2,5-dioxo-4-imidazolidinyl)-
Learn more about Allantoin →Panthenol
Antistatic, Hair Conditioning, Skin Conditioning
Panthenol is panthenol (provitamin B5).
Learn more about Panthenol →Propanediol
Solvent, Viscosity Controlling
Propanediol is the organic compound that conforms to the formula
Learn more about Propanediol →
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