Paula's Choice
Niacinamide 20% TreatmentA serum built around Niacinamide and Vitamin C derivative, for barrier repair and hydration.
A serum built around Panthenol and Niacinamide, for barrier repair and hydration.
Brand price
USD 59.00 · checked 8 Oct 2026 · brand's site
Brand price
Not recorded · brand's site

At a Glance

They come out differently on Oil-free and Vegan; those rows are shaded. Tap any answer to see why.

Key Ingredients


Benefits

Hydrating6
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Butylene Glycol, Camellia Sinensis Leaf Extract, Glycerin, Panthenol, Propanediol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Allantoin, Boerhavia Diffusa Root Extract, Camellia Japonica Flower Extract, Camellia Sinensis Leaf Extract, Glycerin, Glycyrrhiza Glabra Root Extract, Lecithin, Niacinamide, Panthenol
Reduces Irritation4
Eases discomfort and supports skin resilience.
Allantoin, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Panthenol
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Ectoin, Glycerin, Panthenol, Propanediol, Squalane
Barrier Repair7
Strengthens and restores the skin's natural barrier.
Allantoin, Cetearyl Olivate, Glycerin, Limnanthes Alba Seed Oil, Niacinamide, Panthenol, Squalane

Concerns

May Worsen Seborrheic Dermatitis2
May feed the yeast involved in seborrheic dermatitis.
May Worsen Seborrheic Dermatitis5
May feed the yeast involved in seborrheic dermatitis.
Cetearyl Olivate, Limnanthes Alba Seed Oil, Polyglyceryl-10 Stearate, Sorbitan Isostearate, Sorbitan Olivate
May Worsen Keratosis Pilaris1
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Skin Conditioning
Water (in both products)
Skin Conditioning
Panthenol (in both products)
Skin Conditioning
0 / 0
- Panthenol (provitamin B5)
- Barrier Repair
- Hydrating
- Reduces Irritation
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Allantoin
Skin Conditioning, Skin Protecting, Soothing
Urea, (2,5-dioxo-4-imidazolidinyl)-
Learn more about Allantoin →Panthenol
Antistatic, Hair Conditioning, Skin Conditioning
Panthenol is panthenol (provitamin B5).
Learn more about Panthenol →Propanediol
Solvent, Viscosity Controlling
Propanediol is the organic compound that conforms to the formula
Learn more about Propanediol →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →
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