Paula's Choice
Niacinamide 20% TreatmentSkintific
377 Dark Spot SerumA serum built around Niacinamide and Vitamin C derivative, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for hydration and barrier repair.
Brand price
USD 59.00 · checked 8 Oct 2026 · brand's site
Brand price
AUD 34.90 · checked 5 Oct 2026 · brand's site

At a Glance

They come out differently on Pore-clogger-free, Oil-free and Reef-safe; those rows are shaded. Tap any answer to see why.

Key Ingredients

Chemical sunscreen2
Organic UV filters that absorb UV and release it as heat.
Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Methoxycinnamate
Sunscreen2
Any ingredient acting as a UV filter.
Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Methoxycinnamate

Benefits

Hydrating6
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Butylene Glycol, Camellia Sinensis Leaf Extract, Glycerin, Panthenol, Propanediol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Allantoin, Boerhavia Diffusa Root Extract, Camellia Japonica Flower Extract, Camellia Sinensis Leaf Extract, Glycerin, Glycyrrhiza Glabra Root Extract, Lecithin, Niacinamide, Panthenol
Reduces Irritation4
Eases discomfort and supports skin resilience.
Allantoin, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Panthenol
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating15
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Ectoin, Fructose, Glycereth-26, Glycerin, Maris Aqua, Pancratium Maritimum Extract, Simmondsia Chinensis Seed Oil, Sodium Hyaluronate, Squalane, Tocopherol
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Allantoin, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Lecithin, Niacinamide, Pancratium Maritimum Extract, Simmondsia Chinensis Seed Oil, Squalane, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis2
May feed the yeast involved in seborrheic dermatitis.
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
Acetyl Glucosamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ceramide NP, Hydrogenated Lecithin, Lecithin, Phosphatidylcholine, Polysorbate 80, Simmondsia Chinensis Seed Oil, Sodium Stearoyl Glutamate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Acetyl Glucosamine (in both products)
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Portulaca Oleracea Extract (in both products)
Skin Conditioning
Water (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Antioxidant
Skin Conditioning
Acetyl Glucosamine (in both products)
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Acetyl Glucosamine
Skin Conditioning
Acetyl Glucosamine isn't fungal acne safe.
Learn more about Acetyl Glucosamine →Portulaca Oleracea Extract
Skin Conditioning
Portulaca Oleracea Extract is an extract of the whole plant of the Purselane, Portulaca oleracea L., Portulacaceae
Learn more about Portulaca Oleracea Extract →Allantoin
Skin Conditioning, Skin Protecting, Soothing
Urea, (2,5-dioxo-4-imidazolidinyl)-
Learn more about Allantoin →Lecithin
Antistatic, Skin Conditioning, Emollient, Emulsifying
Lecithin isn't fungal acne safe.
Learn more about Lecithin →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →
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