Dr.Althea
345 Relief SerumA serum built around Centella asiatica and Niacinamide, for soothing irritation and barrier repair.
A serum built around Niacinamide and Panthenol, for hydration and barrier repair.
Brand price
Not recorded · brand's site
Brand price
USD 22.00 · checked 26 Sept 2026 · brand's site

At a Glance

They come out differently on Vegan and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Centella asiatica (Cica)6
Centella asiatica (cica), used to calm irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Callus Extracellular Vesicles, Centella Asiatica Extract, Madecassic Acid, Madecassoside
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Centella asiatica (Cica)5
Centella asiatica (cica), used to calm irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Madecassoside
Hyaluronic acid3
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer

Benefits

Hydrating9
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Camellia Sinensis Leaf Extract, Ceramide NP, Dipotassium Glycyrrhizate, Glycerin, Pancratium Maritimum Extract, Panthenol, Propanediol, Sodium Hyaluronate
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Allantoin, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Ceramide NP, Glycerin, Glyceryl Stearate, Niacinamide, Pancratium Maritimum Extract, Panthenol, Sucrose Stearate
Reduces Irritation11
Eases discomfort and supports skin resilience.
Allantoin, Asiatic Acid, Asiaticoside, Camellia Sinensis Leaf Extract, Centella Asiatica Callus Extracellular Vesicles, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Madecassic Acid, Madecassoside, Palmitoyl Tetrapeptide-7, Panthenol
Redness Reducing8
Soothes visible redness and calms irritation.
Allantoin, Asiatic Acid, Asiaticoside, Centella Asiatica Callus Extracellular Vesicles, Centella Asiatica Extract, Madecassic Acid, Madecassoside, Niacinamide
Hydrating13
Boosts hydration and relieves dry, tight skin.
Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Panthenol, Polyglutamic Acid, Propanediol, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Xylose
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Caprylic/Capric Triglyceride, Caprylyl Glycol, Centella Asiatica Extract, Ceramide NP, Cholesterol, Glycerin, Glyceryl Caprylate, Hydrogenated Polydecene, Niacinamide, Panthenol, Resveratrol
Reduces Irritation7
Eases discomfort and supports skin resilience.
Asiatic Acid, Asiaticoside, Beta-Glucan, Centella Asiatica Extract, Madecassic Acid, Madecassoside, Panthenol
Redness Reducing6
Soothes visible redness and calms irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Madecassoside, Niacinamide

Concerns

May Worsen Seborrheic Dermatitis12
May feed the yeast involved in seborrheic dermatitis.
Ceramide NP, Glyceryl Stearate, Hydrogenated Lecithin, Hydrolyzed Jojoba Esters, Palmitoyl Dipeptide-10, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Polyglyceryl-10 Laurate, Polyglyceryl-10 Myristate, Polyglyceryl-10 Stearate, Sucrose Stearate
May Worsen Seborrheic Dermatitis8
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aluminum/Magnesium Hydroxide Stearate, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Hydrogenated Lecithin, Lysolecithin, Phosphatidylcholine

Ingredients Side-by-side

Skin Conditioning
Centella Asiatica Extract (in both products)
Cleansing
- Centella asiatica (Cica)
- Barrier Repair
- Redness Reducing
- Reduces Irritation
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Panthenol (in both products)
Skin Conditioning
0 / 0
- Panthenol (provitamin B5)
- Barrier Repair
- Hydrating
- Reduces Irritation
Betula Platyphylla Japonica Juice
Skin Conditioning
Melaleuca Alternifolia Leaf Water
Antimicrobial
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Panthenol (in both products)
Skin Conditioning
0 / 0
- Panthenol (provitamin B5)
- Barrier Repair
- Hydrating
- Reduces Irritation
1,2-Hexanediol (in both products)
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dipropylene Glycol
Fragrance, Perfuming, Solvent, Viscosity Controlling
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
Learn more about Dipropylene Glycol →Propanediol
Solvent, Viscosity Controlling
Propanediol is the organic compound that conforms to the formula
Learn more about Propanediol →Centella Asiatica Extract
Cleansing, Skin Conditioning, Smoothing, Soothing, Tonic
Centella Asiatica Extract is centella (cica).
Learn more about Centella Asiatica Extract →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Panthenol
Antistatic, Hair Conditioning, Skin Conditioning
Panthenol is panthenol (provitamin B5).
Learn more about Panthenol →Madecassoside
Antioxidant, Skin Conditioning
Madecassoside is centella (cica).
Learn more about Madecassoside →
Similar Comparisons
Each product against its closest dupes.
- View the comparison

Purito
Wonder Releaf Centella Serum Unscented

Purito
Wonder Releaf Centella Serum
- View the comparison

Dr.Althea
345 Relief Serum

Skin1004
Probio-Cica Intensive Ampoule
- View the comparison

Purito
Wonder Releaf Centella Serum Unscented

VT Cosmetics
Hydrop reedle shot 100
- View the comparison

Dr.Althea
345 Relief Serum

COSRX
5 PDRN Collagen Intense Vitalizing Serum