SkinCeuticals
Discoloration Defense Serum for Dark SpotsDr.Althea
345 Relief SerumA serum built around Niacinamide and Tranexamic acid, for barrier repair and hydration.
A serum built around Niacinamide and Panthenol, for hydration and barrier repair.
Brand price
USD 115.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 22.00 · checked 26 Sept 2026 · brand's site

At a Glance

They come out differently on Fungal-acne-safe; that row is shaded. Tap any answer to see why.

Key Ingredients

Centella asiatica (Cica)5
Centella asiatica (cica), used to calm irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Madecassoside
Hyaluronic acid3
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer

Benefits

Hydrating4
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Glycerin, Hydroxyethyl Urea, Propylene Glycol
Barrier Repair5
Strengthens and restores the skin's natural barrier.
Allantoin, Caprylyl Glycol, Glycerin, Niacinamide, Propylene Glycol
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating13
Boosts hydration and relieves dry, tight skin.
Beta-Glucan, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Panthenol, Polyglutamic Acid, Propanediol, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Xylose
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Caprylic/Capric Triglyceride, Caprylyl Glycol, Centella Asiatica Extract, Ceramide NP, Cholesterol, Glycerin, Glyceryl Caprylate, Hydrogenated Polydecene, Niacinamide, Panthenol, Resveratrol
Reduces Irritation7
Eases discomfort and supports skin resilience.
Asiatic Acid, Asiaticoside, Beta-Glucan, Centella Asiatica Extract, Madecassic Acid, Madecassoside, Panthenol
Redness Reducing6
Soothes visible redness and calms irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Madecassoside, Niacinamide

Concerns

No concerns found
May Worsen Seborrheic Dermatitis8
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aluminum/Magnesium Hydroxide Stearate, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Hydrogenated Lecithin, Lysolecithin, Phosphatidylcholine

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Humectant
Betula Platyphylla Japonica Juice
Skin Conditioning
Melaleuca Alternifolia Leaf Water
Antimicrobial
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Disodium EDTA
Chelating, Viscosity Controlling
Disodium dihydrogen ethylenediaminetetraacetate
Learn more about Disodium EDTA →
Similar Comparisons
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Discoloration Defense Serum for Dark Spots

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345 Relief Serum

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Discoloration Defense Serum for Dark Spots

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Dr.Althea
345 Relief Serum

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