SkinCeuticals
Discoloration Defense Serum for Dark SpotsA serum built around Niacinamide and Tranexamic acid, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for hydration and barrier repair.
Brand price
USD 115.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 24.99 · checked 5 Oct 2026 · brand's site

At a Glance

They come out differently on Fungal-acne-safe and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.

Benefits

Hydrating4
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Glycerin, Hydroxyethyl Urea, Propylene Glycol
Barrier Repair5
Strengthens and restores the skin's natural barrier.
Allantoin, Caprylyl Glycol, Glycerin, Niacinamide, Propylene Glycol
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating11
Boosts hydration and relieves dry, tight skin.
Anhydroxylitol, Butylene Glycol, Glucose, Glycerin, Hydrolyzed Hyaluronic Acid, Panthenol, Propanediol, Propylene Glycol, Sodium Hyaluronate, Xylitol, Xylitylglucoside
Barrier Repair7
Strengthens and restores the skin's natural barrier.
Caprylyl Glycol, Glycerin, Niacinamide, Panax Ginseng Root Extract, Panthenol, Propylene Glycol, Xylitol

Concerns

No concerns found
May Worsen Seborrheic Dermatitis2
May feed the yeast involved in seborrheic dermatitis.

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Humectant
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
PEG-40 Hydrogenated Castor Oil
Cleansing
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Humectant
Humectant
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Propylene Glycol
Fragrance, Humectant, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Propylene Glycol is the aliphatic alcohol that conforms generally to the formula
Learn more about Propylene Glycol →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →
Similar Comparisons
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SkinCeuticals
Discoloration Defense Serum for Dark Spots

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SkinCeuticals
Discoloration Defense Serum for Dark Spots

The Derma Co
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