SkinCeuticals
P-TIOX Anti-Wrinkle CreamA face cream built around Niacinamide and Zinc salt, for barrier repair and smoothing.
A face cream built around Niacinamide and Panthenol, for barrier repair and smoothing.
Brand price
USD 150.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 35.00 · checked 25 Sept 2026 · brand's site
At a Glance
They come out differently on Fragrance-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Tocopherol, Zinc PCA
Barrier Repair14
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Dicaprylyl Carbonate, Glycerin, Isododecane, Macadamia Integrifolia Seed Oil, Niacinamide, Palmitic Acid, Tocopherol
Reduces Irritation2
Eases discomfort and supports skin resilience.
Hydrating9
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Caprylic/Capric Triglyceride, Collagen, Glycerin, Helianthus Annuus Seed Oil, Hydrolyzed Collagen, Panthenol, Squalane, Tocopherol
Barrier Repair23
Strengthens and restores the skin's natural barrier.
Behenyl Alcohol, Bis-Diglyceryl Polyacyladipate-2, Brassica Campestris Sterols, C12-16 Alcohols, Caprylic/Capric Triglyceride, Cholesterol, Copernicia Cerifera Wax, Glycerin, Glyceryl Stearate, Helianthus Annuus Seed Oil, Hexyldecyl Myristoyl Methylaminopropionate, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polyisobutene, Hydrolyzed Collagen, Isononyl Isononanoate, Macadamia Ternifolia Seed Oil, Niacinamide, Palmitic Acid, Panthenol, Pentaerythrityl Tetraethylhexanoate, Polyglyceryl-6 Stearate, Squalane, Tocopherol
Concerns
May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter, C12-16 Alcohols, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Glyceryl Stearate Se, Hydrogenated Lecithin, Macadamia Integrifolia Seed Oil, Palmitic Acid, Palmitoyl Tetrapeptide-10, Polysorbate 80, Sorbitan Stearate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Oily Skin2
May increase shine or excess oil.
Butyrospermum Parkii Butter, Macadamia Integrifolia Seed Oil
May Worsen Seborrheic Dermatitis21
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aluminum/Magnesium Hydroxide Stearate, Behenyl Alcohol, Bis-Diglyceryl Polyacyladipate-2, C12-16 Alcohols, Castor Oil/Ipdi Copolymer, Copernicia Cerifera Wax, Glyceryl Stearate, Helianthus Annuus Seed Oil, Hexyldecyl Myristoyl Methylaminopropionate, Hydrogenated Lecithin, Macadamia Ternifolia Seed Oil, Palmitic Acid, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Polyacrylate Crosspolymer-6, Polyglyceryl-10 Laurate, Polyglyceryl-6 Behenate, Polyglyceryl-6 Stearate, Potassium Cetyl Phosphate, Sodium Stearoyl Glutamate, Sorbitan Oleate
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Oily Skin3
May increase shine or excess oil.
Helianthus Annuus Seed Oil, Macadamia Ternifolia Seed Oil, Squalane
Ingredients Side-by-side
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
1,2-Hexanediol (in both products)
Skin Conditioning
Emollient
Skin Conditioning
Skin Conditioning
Emollient
1,2-Hexanediol (in both products)
Skin Conditioning
Film Forming
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
0 / 0
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Pentylene Glycol
Skin Conditioning, Solvent
1,2-Dihydroxypentane
Learn more about Pentylene Glycol →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Vinyl Dimethicone
Viscosity Controlling
Vinyl Dimethicone is a silicone.
Learn more about Vinyl Dimethicone →Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion Stabilising, Film Forming, Viscosity Controlling
Acrylates/C10-30 Alkyl Acrylate Crosspolymer isn't fungal acne safe.
Learn more about Acrylates/C10-30 Alkyl Acrylate Crosspolymer →C12-16 Alcohols
Antistatic, Emulsion Stabilising, Hair Conditioning, Emollient, Viscosity Controlling
C12-16 Alcohols isn't fungal acne safe.
Learn more about C12-16 Alcohols →Tromethamine
Buffering, Fragrance
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about Tromethamine →
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