SkinCeuticals
P-TIOX Anti-Wrinkle CreamA face cream built around Niacinamide and Zinc salt, for barrier repair and smoothing.
A face cream built around Ceramide and Niacinamide, for barrier repair and hydration.
Brand price
USD 150.00 · checked 28 Sept 2026 · brand's site
Brand price
Not recorded · brand's site

At a Glance

They come out differently on Cruelty-free; that row is shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol2
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Ceramide3
Skin-identical lipids that hold the barrier together.

Benefits

Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Tocopherol, Zinc PCA
Barrier Repair14
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Dicaprylyl Carbonate, Glycerin, Isododecane, Macadamia Integrifolia Seed Oil, Niacinamide, Palmitic Acid, Tocopherol
Reduces Irritation2
Eases discomfort and supports skin resilience.
Hydrating12
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Ceramide AP, Ceramide EOP, Ceramide NP, Dimethicone, Glycerin, Saccharide Isomerate, Sodium Hyaluronate, Stearic Acid, Tocopherol
Barrier Repair20
Strengthens and restores the skin's natural barrier.
Allantoin, Butyrospermum Parkii Butter, Caprooyl Tetrapeptide-3, Caprylic/Capric Triglyceride, Ceramide AP, Ceramide EOP, Ceramide NP, Cetearyl Alcohol, Cetyl Alcohol, Cholesterol, Cyclopentasiloxane, Dimethicone, Glycerin, Glycine Soja Sterols, Niacinamide, Palmitic Acid, Phytosphingosine, Stearic Acid, Tocopherol, Tripeptide-1

Concerns

May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter, C12-16 Alcohols, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Glyceryl Stearate Se, Hydrogenated Lecithin, Macadamia Integrifolia Seed Oil, Palmitic Acid, Palmitoyl Tetrapeptide-10, Polysorbate 80, Sorbitan Stearate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Oily Skin2
May increase shine or excess oil.
Butyrospermum Parkii Butter, Macadamia Integrifolia Seed Oil
May Trigger Acne7
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate Se, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol
May Worsen Seborrheic Dermatitis14
May feed the yeast involved in seborrheic dermatitis.
Behentrimonium Methosulfate, Butyrospermum Parkii Butter, Ceramide AP, Ceramide EOP, Ceramide NP, Cetearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate Se, Laureth-9, Myristic Acid, Palmitic Acid, Phytosphingosine, Sodium Lauroyl Lactylate, Stearic Acid
May Worsen Keratosis Pilaris7
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate Se, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
Cetearyl Alcohol (in both products)
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Emollient
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Glyceryl Stearate Se (in both products)
Emulsifying
3 / 2
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
2 / 2
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Cetearyl Alcohol
Emulsion Stabilising, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetearyl Alcohol isn't fungal acne safe.
Learn more about Cetearyl Alcohol →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Glyceryl Stearate Se
Emulsifying
Glyceryl Stearate Se may be plant, synthetic or animal depending on the supplier.
Learn more about Glyceryl Stearate Se →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →
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