SkinCeuticals
P-TIOX Anti-Wrinkle CreamA face cream built around Niacinamide and Zinc salt, for barrier repair and smoothing.
A face cream built around Niacinamide and Copper peptides, for hydration and barrier repair.
Brand price
USD 150.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 28.00 · checked 25 Sept 2026 · brand's site

At a Glance

They come out differently on Oil-free; that row is shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Tocopherol, Zinc PCA
Barrier Repair14
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Dicaprylyl Carbonate, Glycerin, Isododecane, Macadamia Integrifolia Seed Oil, Niacinamide, Palmitic Acid, Tocopherol
Reduces Irritation2
Eases discomfort and supports skin resilience.
Hydrating22
Boosts hydration and relieves dry, tight skin.
Acetyl Heptapeptide-4, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Beta-Glucan, Betaine, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Dimethicone, Glycerin, Hyaluronic Acid, Hydrolyzed Collagen, Hydrolyzed Hyaluronic Acid, Inositol, Panthenol, Propanediol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Squalane, Stearic Acid, Tocopherol
Barrier Repair20
Strengthens and restores the skin's natural barrier.
Bakuchiol, Betaine, C30-45 Alkyl Cetearyl Dimethicone Crosspolymer, Caprylic/Capric Triglyceride, Caprylyl Glycol, Ceramide NP, Cetearyl Alcohol, Cholesterol, Dimethicone, Glycerin, Glyceryl Caprylate, Glyceryl Stearate, Hydrolyzed Collagen, Niacinamide, Palmitic Acid, Panthenol, Squalane, Stearic Acid, Synthetic Wax, Tocopherol

Concerns

May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter, C12-16 Alcohols, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Glyceryl Stearate Se, Hydrogenated Lecithin, Macadamia Integrifolia Seed Oil, Palmitic Acid, Palmitoyl Tetrapeptide-10, Polysorbate 80, Sorbitan Stearate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Oily Skin2
May increase shine or excess oil.
Butyrospermum Parkii Butter, Macadamia Integrifolia Seed Oil
May Trigger Acne6
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Lauric Acid, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol
May Worsen Seborrheic Dermatitis18
May feed the yeast involved in seborrheic dermatitis.
Acetyl Heptapeptide-4, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Ceramide NP, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Hydrogenated Lecithin, Lauric Acid, Myristic Acid, Palmitic Acid, Polyacrylate Crosspolymer-6, Polyglyceryl-10 Stearate, Polyglyceryl-3 Methylglucose Distearate, Sodium Acetylated Hyaluronate, Stearic Acid
May Worsen Keratosis Pilaris6
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Lauric Acid, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
Cetearyl Alcohol (in both products)
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
1,2-Hexanediol (in both products)
Skin Conditioning
Emollient
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Cetearyl Alcohol (in both products)
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Cetearyl Alcohol
Emulsion Stabilising, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetearyl Alcohol isn't fungal acne safe.
Learn more about Cetearyl Alcohol →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →
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