SkinCeuticals
P-TIOX Anti-Wrinkle CreamA face cream built around Niacinamide and Zinc salt, for barrier repair and smoothing.
A face cream built around Niacinamide, for hydration and barrier repair.
Brand price
USD 150.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 23.00 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, EU-allergen-free and Pore-clogger-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol2
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Hyaluronic acid3
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer

Benefits

Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Tocopherol, Zinc PCA
Barrier Repair14
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Dicaprylyl Carbonate, Glycerin, Isododecane, Macadamia Integrifolia Seed Oil, Niacinamide, Palmitic Acid, Tocopherol
Reduces Irritation2
Eases discomfort and supports skin resilience.
Hydrating17
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Collagen Water, Dimethicone, Glucose, Glycerin, Glyceryl Glucoside, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Propanediol, Simmondsia Chinensis Seed Oil, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Squalane, Stearyl Alcohol
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Arachidyl Alcohol, Behenyl Alcohol, Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Citrus Junos Fruit Oil, Dimethicone, Glycerin, Glyceryl Stearate, Niacinamide, Olea Europaea Fruit Oil, Palmitic Acid, Simmondsia Chinensis Seed Oil, Squalane, Stearyl Alcohol

Concerns

May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter, C12-16 Alcohols, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Glyceryl Stearate Se, Hydrogenated Lecithin, Macadamia Integrifolia Seed Oil, Palmitic Acid, Palmitoyl Tetrapeptide-10, Polysorbate 80, Sorbitan Stearate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Oily Skin2
May increase shine or excess oil.
Butyrospermum Parkii Butter, Macadamia Integrifolia Seed Oil
May Trigger Acne5
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Olea Europaea Fruit Oil, Palmitic Acid, Simmondsia Chinensis Seed Oil, Stearyl Alcohol
May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Lecithin, Olea Europaea Fruit Oil, Palmitic Acid, Polyglyceryl-10 Laurate, Polyglyceryl-2 Stearate, Simmondsia Chinensis Seed Oil, Sodium Acetylated Hyaluronate, Stearyl Alcohol
May Worsen Keratosis Pilaris5
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Olea Europaea Fruit Oil, Palmitic Acid, Simmondsia Chinensis Seed Oil, Stearyl Alcohol
May Worsen Oily Skin4
May increase shine or excess oil.
Butyrospermum Parkii Butter, Olea Europaea Fruit Oil, Simmondsia Chinensis Seed Oil, Squalane

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
Cetearyl Alcohol (in both products)
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
1,2-Hexanediol (in both products)
Skin Conditioning
Emollient
Skin Conditioning
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Cetearyl Alcohol
Emulsion Stabilising, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetearyl Alcohol isn't fungal acne safe.
Learn more about Cetearyl Alcohol →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →C12-16 Alcohols
Antistatic, Emulsion Stabilising, Hair Conditioning, Emollient, Viscosity Controlling
C12-16 Alcohols isn't fungal acne safe.
Learn more about C12-16 Alcohols →Tromethamine
Buffering, Fragrance
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about Tromethamine →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →
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