SkinCeuticals
P-TIOX Anti-Wrinkle CreamA face cream built around Niacinamide and Zinc salt, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and hydration.
Brand price
USD 150.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 32.00 · checked 26 Sept 2026 · brand's site

At a Glance

Every check both products could be assessed on comes out the same. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Vitamin C (L-ascorbic acid)1
L-ascorbic acid, the unesterified form of vitamin C.

Benefits

Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Tocopherol, Zinc PCA
Barrier Repair14
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Camellia Sinensis Leaf Extract, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Dicaprylyl Carbonate, Glycerin, Isododecane, Macadamia Integrifolia Seed Oil, Niacinamide, Palmitic Acid, Tocopherol
Reduces Irritation2
Eases discomfort and supports skin resilience.
Hydrating14
Boosts hydration and relieves dry, tight skin.
Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-5, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Hyaluronic Acid, Hydrolyzed Collagen, Sorbitol, Stearic Acid, Tocopherol
Barrier Repair18
Strengthens and restores the skin's natural barrier.
Acetyl Tetrapeptide-3, Brassica Campestris Sterols, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cholesterol, Diethylhexyl Syringylidenemalonate, Dimethicone, Glycerin, Glyceryl Stearate, Hydrogenated Polyisobutene, Hydrolyzed Collagen, Lecithin, Macadamia Ternifolia Seed Oil, Niacinamide, Palmitic Acid, Stearic Acid, Tocopherol

Concerns

May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Seborrheic Dermatitis15
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter, C12-16 Alcohols, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide NP, Cetearyl Alcohol, Cetyl Palmitate, Glyceryl Stearate Se, Hydrogenated Lecithin, Macadamia Integrifolia Seed Oil, Palmitic Acid, Palmitoyl Tetrapeptide-10, Polysorbate 80, Sorbitan Stearate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glyceryl Stearate Se, Palmitic Acid, Tocopherol
May Worsen Oily Skin2
May increase shine or excess oil.
Butyrospermum Parkii Butter, Macadamia Integrifolia Seed Oil
May Trigger Acne4
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-9, Aluminum/Magnesium Hydroxide Stearate, Ceramide NP, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Lecithin, Lecithin, Macadamia Ternifolia Seed Oil, Palmitic Acid, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Polyglyceryl-10 Laurate, Polyglyceryl-3 Methylglucose Distearate, Potassium Cetyl Phosphate, Stearic Acid
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
Cetearyl Alcohol (in both products)
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
1,2-Hexanediol (in both products)
Skin Conditioning
Emollient
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
1,2-Hexanediol (in both products)
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Pentylene Glycol
Skin Conditioning, Solvent
1,2-Dihydroxypentane
Learn more about Pentylene Glycol →Cetearyl Alcohol
Emulsion Stabilising, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetearyl Alcohol isn't fungal acne safe.
Learn more about Cetearyl Alcohol →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Vinyl Dimethicone
Viscosity Controlling
Vinyl Dimethicone is a silicone.
Learn more about Vinyl Dimethicone →Tromethamine
Buffering, Fragrance
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about Tromethamine →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →
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