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La Roche-Posay
Mela B3 Double Dose Discoloration Treatment with Melasyl™
A serum built around Niacinamide, for barrier repair and smoothing.
Brand price
USD 54.99 · checked 25 Sept 2026 · on the brand's site
From the brand
What the brand says about this product. Our ingredient analysis follows below.
The brand recommends it for
- Normal skin
- Dark spots & pigmentation
- Fine lines & wrinkles
- Dullness
How to use
3-4 pumps Apply morning and evening on clean skin Apply on face, neck, decollete and hands Apply Mela B3 Double Dose after cleansing skin, targeting and treating areas of discoloration
What's inside
Ingredients List
11 trigger at least one check · 23 trigger none
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating5
Boosts hydration and relieves dry, tight skin.
Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Tocopherol
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Caprylyl Glycol, Cetearyl Alcohol, Dimethicone, Glycerin, Glycine Soja Oil, Neopentyl Glycol Dicaprate, Niacinamide, Octyldodecanol, Propylene Glycol, Sucrose Tristearate, Tocopherol
Smoothing9
Refines rough or uneven texture.
Caprylyl Glycol, Cetearyl Alcohol, Citric Acid, Dimethicone, Glycine Soja Oil, Neopentyl Glycol Dicaprate, Niacinamide, Octyldodecanol, Sucrose Tristearate
Antioxidant2
Shields skin from free radical damage.
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Tocopherol
Anti-Pollution4
Helps defend against airborne pollutants.
Dimethicone, Glycerin, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Tocopherol
Concerns
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Glycine Soja Oil, Hydrogenated Lecithin, Octyldodecanol, Sodium Stearoyl Glutamate, Sucrose Tristearate
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Explained
Click on any ingredient to learn more about it
Aqua
Solvent
Neopentyl Glycol Dicaprate
Skin Conditioning, Emollient
2,2-Dimethyl-1,3-propanediyl didecanoate
Learn more about Neopentyl Glycol Dicaprate →Alcohol Denat.
Antifoaming, Antimicrobial, Astringent, Fragrance, Solvent, Viscosity Controlling
Alcohol Denat. is a drying alcohol.
Learn more about Alcohol Denat. →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Hydroxypropyl Tetrahydropyrantriol
Skin Conditioning
L-Gluco-Octitol, 1,5-Anhydro-6,8-dideoxy-, (7xi)-
Learn more about Hydroxypropyl Tetrahydropyrantriol →Sucrose Tristearate
Skin Conditioning, Emollient, Emulsifying
Sucrose Tristearate isn't fungal acne safe.
Learn more about Sucrose Tristearate →Cetearyl Alcohol
Emulsion Stabilising, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetearyl Alcohol isn't fungal acne safe.
Learn more about Cetearyl Alcohol →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →2-Mercaptonicotinoyl Glycine
Skin Conditioning
2-Mercaptonicotinoyl Glycine is the organic compound that conforms to the formula
Learn more about 2-Mercaptonicotinoyl Glycine →
Dupes
- La Roche-Posay Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide75% match
- La Roche-Posay Retinol B3 Pure Retinol Serum70% match
- SkinCeuticals Hyaluronic Acid Intensifier Multi-Glycan69% match
- Kiehl's Age Defender Power Serum For Men62% match
- CeraVe Skin Renewing Super Boost Serum62% match
- SkinCeuticals Antioxidant Resveratrol B E Nighttime Serum61% match