
Image: paulaschoice.com
Paula's Choice
25% Vitamin C + Glutathione Clinical Serum
A serum built around Vitamin C derivative and Vitamin C, for hydration and barrier repair.
Brand price
USD 70.00 · checked 8 Oct 2026 · on the brand's site
From the brand
What the brand says about this product. Our ingredient analysis follows below.
The brand recommends it for
- Dry skin
- Oily skin
- Combination skin
- Normal skin
- Sensitive skin
- Acne & blemishes
- Redness & rosacea
- Dark spots & pigmentation
- Fine lines & wrinkles
- Dryness & dehydration
- Dullness
How to use
Apply vitamin C serum onto face and neck. For optimal results, use AM and PM. For daytime, follow with SPF 30+ .
What's inside
Ingredients List
10 trigger at least one check · 31 trigger none
- Fatty alcohols (Malassezia)
- Vitamin C
- Vitamin C derivative (stable)
- Antioxidant
- Brightening
- Dark Spots
- May Worsen Seborrheic Dermatitis
- Vitamin C
- Vitamin C derivative (stable)
- Antioxidant
- Brightening
- Dark Spots
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Vitamin C derivative (stable)2
Stable derivatives of ascorbic acid.
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Vitamin C3
Vitamin C in any form: an antioxidant and brightener.
Ascorbic Acid, Ascorbyl Glucoside, Tetrahexyldecyl Ascorbate
Benefits
Hydrating11
Boosts hydration and relieves dry, tight skin.
C9-12 Alkane, Caprylic/Capric Triglyceride, Dimethicone, Glucose, Glycerin, Mannitol, Sodium Hyaluronate, Sodium PCA, Tocopherol, Trehalose, Urea
Barrier Repair10
Strengthens and restores the skin's natural barrier.
C9-12 Alkane, Caprylic/Capric Triglyceride, Caprylyl Glycol, Cetyl Alcohol, Coco-Caprylate/Caprate, Dimethicone, Glycerin, Oryza Sativa Bran Extract, Tocopherol, Vanilla Planifolia Fruit Extract
Smoothing6
Refines rough or uneven texture.
C9-12 Alkane, Caprylyl Glycol, Cetyl Alcohol, Coco-Caprylate/Caprate, Dimethicone, Vanilla Planifolia Fruit Extract
Brightening4
Restores radiance to dull, tired skin.
Ascorbic Acid, Ascorbyl Glucoside, Glutathione, Tetrahexyldecyl Ascorbate
Dark Spots3
Fades dark spots for a more even tone.
Ascorbic Acid, Ascorbyl Glucoside, Tetrahexyldecyl Ascorbate
Antioxidant5
Shields skin from free radical damage.
Ascorbic Acid, Ascorbyl Glucoside, Ergothioneine, Tetrahexyldecyl Ascorbate, Tocopherol
Anti-Pollution9
Helps defend against airborne pollutants.
Ascorbic Acid, Ascorbyl Glucoside, Dimethicone, Ergothioneine, Glycerin, Oryza Sativa Bran Extract, Tetrahexyldecyl Ascorbate, Tocopherol, Vanilla Planifolia Fruit Extract
Concerns
May Trigger Acne4
Can clog pores or trigger breakouts.
Cetyl Alcohol, Hexylene Glycol, Sorbitan Isostearate, Tocopherol
May Worsen Seborrheic Dermatitis8
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetyl Alcohol, Coco-Caprylate/Caprate, Hydrogenated Lecithin, Polyglyceryl-6 Polyricinoleate, Polysorbate 60, Sorbitan Isostearate, Tetrahexyldecyl Ascorbate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetyl Alcohol, Hexylene Glycol, Sorbitan Isostearate, Tocopherol
Ingredients Explained
Click on any ingredient to learn more about it
Aqua
Solvent
Tetrahexyldecyl Ascorbate
Antioxidant, Skin Conditioning
Tetrahexyldecyl Ascorbate isn't fungal acne safe.
Learn more about Tetrahexyldecyl Ascorbate →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →C9-12 Alkane
Hair Conditioning, Emollient, Skin Conditioning, Occlusive, Solvent
C9-12 Alkane is a mixture of linear alkanes with 9 to 12 carbon atoms in the alkyl chain.
Learn more about C9-12 Alkane →Ascorbyl Glucoside
Antioxidant
Ascorbyl Glucoside is a vitamin C derivative.
Learn more about Ascorbyl Glucoside →Silica
Abrasive, Absorbent, Anticaking, Bulking, Opacifying, Viscosity Controlling
Silicon dioxide
Learn more about Silica →Pyrus Malus Fruit Extract
Skin Conditioning
Pyrus Malus Fruit Extract is an extract of the fruit of the Apple, Pyrus malus L., Rosaceae
Learn more about Pyrus Malus Fruit Extract →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Polyglyceryl-6 Polyricinoleate
Emulsifying
Polyglyceryl-6 Polyricinoleate isn't fungal acne safe.
Learn more about Polyglyceryl-6 Polyricinoleate →