
Image: skinceuticals.com
SkinCeuticals
Advanced RGN-6
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 195.00 · checked 28 Sept 2026 · on the brand's site
From the brand
What the brand says about this product. Our ingredient analysis follows below.
The brand recommends it for
- Combination skin
- Sensitive skin
- Acne & blemishes
- Dark spots & pigmentation
- Fine lines & wrinkles
How to use
Once or twice daily after cleansing, apply 1-2 pumps of Advanced RGN-6 to the palm of the hand and press into the skin of the forehead cheeks and chin. Blend the product into the skin. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen.
What's inside
Ingredients List
11 trigger at least one check · 18 trigger none
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Smoothing10
Refines rough or uneven texture.
C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Citric Acid, Dimethicone, Ethyl Oleate, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane
Anti-Pollution4
Helps defend against airborne pollutants.
Dimethicone, Eperua Falcata Bark Extract, Glycerin, Tocopherol
Concerns
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Explained
Click on any ingredient to learn more about it
Aqua
Solvent
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Ethyl Oleate
Perfuming, Emollient
Ethyl Oleate isn't fungal acne safe.
Learn more about Ethyl Oleate →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →C12-16 Alcohols
Antistatic, Emulsion Stabilising, Hair Conditioning, Emollient, Viscosity Controlling
C12-16 Alcohols isn't fungal acne safe.
Learn more about C12-16 Alcohols →Glyceryl Stearate Citrate
Skin Conditioning, Emollient, Emulsifying
Glyceryl Stearate Citrate isn't fungal acne safe.
Learn more about Glyceryl Stearate Citrate →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →Maltodextrin
Absorbent, Binding, Emulsion Stabilising, Film Forming, Hair Conditioning, Skin Conditioning
Maltodextrin
Learn more about Maltodextrin →Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising, Viscosity Controlling
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-, monoammonium salt, homopolymer
Learn more about Ammonium Polyacryloyldimethyl Taurate →
Dupes
- La Roche-Posay Toleriane Double Repair Face Moisturizer66% match
- Rejuran Triple Radiance Cream64% match
- La Roche-Posay Toleriane Dermallergo Night Moisturizer64% match
- CeraVe Skin Renewing Night Cream64% match
- La Roche-Posay Lipikar AP+MAX Triple Repair Moisturizing Cream for Face & Body63% match
- First Aid Beauty Ultra Repair Firming Day Cream with Peptides, Niacinamide + Collagen63% match