La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + NiacinamideLa Roche-Posay
Retinol B3 Pure Retinol SerumA serum built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for smoothing and barrier repair.
Brand price
USD 60.99 · checked 25 Sept 2026 · brand's site
Brand price
USD 44.99 · checked 25 Sept 2026 · brand's site

At a Glance

They come out differently on Alcohol-free and Oil-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.

Benefits

Hydrating7
Boosts hydration and relieves dry, tight skin.
Caprylic/Capric Triglyceride, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Dimethicone, Glycerin, Niacinamide, Octyldodecanol, Propylene Glycol, Tocopherol
Hydrating4
Boosts hydration and relieves dry, tight skin.
Barrier Repair7
Strengthens and restores the skin's natural barrier.
Caprylyl Glycol, Cyclohexasiloxane, Dimethicone, Glycerin, Glycine Soja Oil, Niacinamide, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Retinyl Palmitate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Irritation3
May cause stinging, redness or sensitivity.
May Trigger Acne3
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Glycine Soja Oil, PPG-6-DECYLTETRADECETH-30, Retinyl Palmitate
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Cystoseira Tamariscifolia Extract
Skin Conditioning
Skin Conditioning
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
3 / 0
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Polysilicone-11
Film Forming
Polysilicone-11 is a silicone.
Learn more about Polysilicone-11 →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising, Viscosity Controlling
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-, monoammonium salt, homopolymer
Learn more about Ammonium Polyacryloyldimethyl Taurate →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →Trisodium Ethylenediamine Disuccinate
Chelating
L-Aspartic acid, N,N'-1,2-ethanediylbis-, trisodium salt
Learn more about Trisodium Ethylenediamine Disuccinate →
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