La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + NiacinamideA serum built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
A serum built around Niacinamide, for barrier repair and smoothing.
Brand price
USD 60.99 · checked 25 Sept 2026 · brand's site
Brand price
USD 54.99 · checked 25 Sept 2026 · brand's site
At a Glance
They come out differently on Alcohol-free and Oil-free; those rows are shaded. Tap any answer to see why.
Key Ingredients
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating7
Boosts hydration and relieves dry, tight skin.
Caprylic/Capric Triglyceride, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Dimethicone, Glycerin, Niacinamide, Octyldodecanol, Propylene Glycol, Tocopherol
Hydrating5
Boosts hydration and relieves dry, tight skin.
Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Tocopherol
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Caprylyl Glycol, Cetearyl Alcohol, Dimethicone, Glycerin, Glycine Soja Oil, Neopentyl Glycol Dicaprate, Niacinamide, Octyldodecanol, Propylene Glycol, Sucrose Tristearate, Tocopherol
Concerns
May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Retinyl Palmitate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Irritation3
May cause stinging, redness or sensitivity.
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Glycine Soja Oil, Hydrogenated Lecithin, Octyldodecanol, Sodium Stearoyl Glutamate, Sucrose Tristearate
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Cystoseira Tamariscifolia Extract (in both products)
Skin Conditioning
2-Mercaptonicotinoyl Glycine (in both products)
Skin Conditioning
Emollient
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Hydroxypropyl Tetrahydropyrantriol
Skin Conditioning
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
2-Mercaptonicotinoyl Glycine (in both products)
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Propylene Glycol
Fragrance, Humectant, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Propylene Glycol is the aliphatic alcohol that conforms generally to the formula
Learn more about Propylene Glycol →Cystoseira Tamariscifolia Extract
Skin Conditioning
Cystoseira Tamariscifolia Extract is an extract of the Alga, Cystoseira tamariscifolia, Cystoseiraceae
Learn more about Cystoseira Tamariscifolia Extract →2-Mercaptonicotinoyl Glycine
Skin Conditioning
2-Mercaptonicotinoyl Glycine is the organic compound that conforms to the formula
Learn more about 2-Mercaptonicotinoyl Glycine →Sodium Thiosulfate
Reducing
Sodium thiosulphate
Learn more about Sodium Thiosulfate →Carnosine
Skin Conditioning
L-histidine, N-beta-alanyl
Learn more about Carnosine →Dipotassium Glycyrrhizate
Humectant, Skin Conditioning
.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt
Learn more about Dipotassium Glycyrrhizate →
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