La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + NiacinamidePaula's Choice
1% Retinol BoosterA serum built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
A serum built around Retinoid and Ceramide, for barrier repair and hydration.
Brand price
USD 60.99 · checked 25 Sept 2026 · brand's site
Brand price
USD 55.00 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, Silicone-free, Pore-clogger-free, Oil-free, Vegan and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.

Benefits

Hydrating7
Boosts hydration and relieves dry, tight skin.
Caprylic/Capric Triglyceride, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Dimethicone, Glycerin, Niacinamide, Octyldodecanol, Propylene Glycol, Tocopherol
Hydrating5
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Ceramide NP, Dipotassium Glycyrrhizate, Glycerin, Glyceryl Ascorbate
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Allantoin, Avena Sativa Kernel Extract, Caprylyl Glycol, Carthamus Tinctorius Seed Oil, Ceramide NP, Glycerin
Reduces Irritation3
Eases discomfort and supports skin resilience.
Allantoin, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Retinyl Palmitate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Irritation3
May cause stinging, redness or sensitivity.
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Carthamus Tinctorius Seed Oil, Ceramide NP, Ethylhexyl Olivate, Hydrogenated Lecithin, Palmitoyl Tripeptide-1, Polyglyceryl-10 Laurate, Polysorbate 20

Ingredients Side-by-side

Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Cystoseira Tamariscifolia Extract
Skin Conditioning
Skin Conditioning
Skin Conditioning
Skin Conditioning
0 / 0
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Polyglyceryl-10 Caprylate/Caprate
Cleansing
Skin Conditioning
Cleansing
0 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Polysorbates (Tween emulsifiers)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Retinoid
- Acne Fighting
- Anti-Aging
- Dark Spots
- Firming
- Oil Control
- Pore Refining
- Smoothing
Glycyrrhiza Glabra
Skin Conditioning
- Ceramide
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Barrier Repair
- Hydrating
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dipotassium Glycyrrhizate
Humectant, Skin Conditioning
.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt
Learn more about Dipotassium Glycyrrhizate →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →
Similar Comparisons
Each product against its closest dupes.
- View the comparison

La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide

La Roche-Posay
Mela B3 Double Dose Discoloration Treatment with Melasyl™
- View the comparison

Paula's Choice
1% Retinol Booster

Paula's Choice
1% Retinol Treatment
- View the comparison

La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide

SkinCeuticals
Hyaluronic Acid Intensifier Multi-Glycan
- View the comparison

Paula's Choice
1% Retinol Booster

Isntree
Hyper Retinol EX 1.0 Serum