La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + NiacinamidePaula's Choice
1% Retinol TreatmentA serum built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
A serum built around Vitamin C derivative and Vitamin C, for barrier repair and smoothing.
Brand price
USD 60.99 · checked 25 Sept 2026 · brand's site
Brand price
USD 48.75 · checked 8 Oct 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, Pore-clogger-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.

Benefits

Hydrating7
Boosts hydration and relieves dry, tight skin.
Caprylic/Capric Triglyceride, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Dimethicone, Glycerin, Niacinamide, Octyldodecanol, Propylene Glycol, Tocopherol
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Hydrolyzed Soy Protein, PEG-14, PEG-33, Sodium Hyaluronate
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Allantoin, Arachidyl Alcohol, Avena Sativa Kernel Extract, Behenyl Alcohol, C12-15 Alkyl Benzoate, Caprylyl Glycol, Dimethicone, Glycerin, Glyceryl Stearate, Glycine Soja Sterols, Glycyrrhiza Glabra Root Extract, Isononyl Isononanoate, Lecithin, Pentaerythrityl Tetraisostearate, PPG-12/SMDI Copolymer, Tribehenin
Reduces Irritation5
Eases discomfort and supports skin resilience.
Allantoin, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Palmitoyl Tetrapeptide-7
Redness Reducing2
Soothes visible redness and calms irritation.

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Retinyl Palmitate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Irritation3
May cause stinging, redness or sensitivity.
May Trigger Acne2
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Acetyl Dipeptide-1 Cetyl Ester, Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, C12-15 Alkyl Benzoate, Castor Isostearate Succinate, Ceramide Ng, Glyceryl Stearate, Lecithin, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, PEG-100 Stearate, PEG-75 Shea Butter Glycerides, Pentaerythrityl Tetraisostearate, Polysorbate 20, Sorbitan Laurate, Tetrahexyldecyl Ascorbate, Tribehenin
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Cystoseira Tamariscifolia Extract
Skin Conditioning
Skin Conditioning
Skin Conditioning
Emollient
Skin Conditioning
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Humectant
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →Dipotassium Glycyrrhizate
Humectant, Skin Conditioning
.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt
Learn more about Dipotassium Glycyrrhizate →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Pentylene Glycol
Skin Conditioning, Solvent
1,2-Dihydroxypentane
Learn more about Pentylene Glycol →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →
Similar Comparisons
Each product against its closest dupes.
- View the comparison

La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide

La Roche-Posay
Mela B3 Double Dose Discoloration Treatment with Melasyl™
- View the comparison

Paula's Choice
1% Retinol Treatment

Paula's Choice
1% Retinol Booster
- View the comparison

La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide

SkinCeuticals
Hyaluronic Acid Intensifier Multi-Glycan
- View the comparison

Paula's Choice
1% Retinol Treatment

No7
Pure Retinol 1% Night Concentrate