Paula's Choice
25% Vitamin C + Glutathione Clinical SerumPaula's Choice
1% Retinol TreatmentA serum built around Vitamin C derivative and Vitamin C, for hydration and barrier repair.
A serum built around Vitamin C derivative and Vitamin C, for barrier repair and smoothing.
Brand price
USD 70.00 · checked 8 Oct 2026 · brand's site
Brand price
USD 48.75 · checked 8 Oct 2026 · brand's site
At a Glance
They come out differently on Pore-clogger-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Vitamin C derivative (stable)2
Stable derivatives of ascorbic acid.
Benefits
Hydrating11
Boosts hydration and relieves dry, tight skin.
C9-12 Alkane, Caprylic/Capric Triglyceride, Dimethicone, Glucose, Glycerin, Mannitol, Sodium Hyaluronate, Sodium PCA, Tocopherol, Trehalose, Urea
Barrier Repair10
Strengthens and restores the skin's natural barrier.
C9-12 Alkane, Caprylic/Capric Triglyceride, Caprylyl Glycol, Cetyl Alcohol, Coco-Caprylate/Caprate, Dimethicone, Glycerin, Oryza Sativa Bran Extract, Tocopherol, Vanilla Planifolia Fruit Extract
Smoothing6
Refines rough or uneven texture.
C9-12 Alkane, Caprylyl Glycol, Cetyl Alcohol, Coco-Caprylate/Caprate, Dimethicone, Vanilla Planifolia Fruit Extract
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Hydrolyzed Soy Protein, PEG-14, PEG-33, Sodium Hyaluronate
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Allantoin, Arachidyl Alcohol, Avena Sativa Kernel Extract, Behenyl Alcohol, C12-15 Alkyl Benzoate, Caprylyl Glycol, Dimethicone, Glycerin, Glyceryl Stearate, Glycine Soja Sterols, Glycyrrhiza Glabra Root Extract, Isononyl Isononanoate, Lecithin, Pentaerythrityl Tetraisostearate, PPG-12/SMDI Copolymer, Tribehenin
Reduces Irritation5
Eases discomfort and supports skin resilience.
Allantoin, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Palmitoyl Tetrapeptide-7
Redness Reducing2
Soothes visible redness and calms irritation.
Concerns
May Trigger Acne4
Can clog pores or trigger breakouts.
Cetyl Alcohol, Hexylene Glycol, Sorbitan Isostearate, Tocopherol
May Worsen Seborrheic Dermatitis8
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetyl Alcohol, Coco-Caprylate/Caprate, Hydrogenated Lecithin, Polyglyceryl-6 Polyricinoleate, Polysorbate 60, Sorbitan Isostearate, Tetrahexyldecyl Ascorbate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetyl Alcohol, Hexylene Glycol, Sorbitan Isostearate, Tocopherol
May Trigger Acne2
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Acetyl Dipeptide-1 Cetyl Ester, Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, C12-15 Alkyl Benzoate, Castor Isostearate Succinate, Ceramide Ng, Glyceryl Stearate, Lecithin, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, PEG-100 Stearate, PEG-75 Shea Butter Glycerides, Pentaerythrityl Tetraisostearate, Polysorbate 20, Sorbitan Laurate, Tetrahexyldecyl Ascorbate, Tribehenin
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Tetrahexyldecyl Ascorbate (in both products)
Antioxidant
- Fatty alcohols (Malassezia)
- Vitamin C
- Vitamin C derivative (stable)
- Antioxidant
- Brightening
- Dark Spots
- May Worsen Seborrheic Dermatitis
Emollient
Skin Conditioning
Emulsifying
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Polyglyceryl-6 Polyricinoleate
Emulsifying
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Emollient
Skin Conditioning
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Humectant
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Tetrahexyldecyl Ascorbate
Antioxidant, Skin Conditioning
Tetrahexyldecyl Ascorbate isn't fungal acne safe.
Learn more about Tetrahexyldecyl Ascorbate →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →
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