SkinCeuticals
Advanced RGN-6La Roche-Posay
Toleriane Double Repair Face MoisturizerA face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
A face moisturizer built around Niacinamide and Ceramide, for barrier repair and smoothing.
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 24.99 · checked 25 Sept 2026 · brand's site
At a Glance
They come out differently on Oil-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Hydrating5
Boosts hydration and relieves dry, tight skin.
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Caprylyl Glycol, Ceramide NP, Dimethicone, Glycerin, Myristyl Myristate, Niacinamide, Palmitic Acid, Squalane, Stearic Acid, Zea Mays Starch
Smoothing6
Refines rough or uneven texture.
Caprylyl Glycol, Dimethicone, Myristyl Myristate, Niacinamide, Palmitic Acid, Squalane
Concerns
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Trigger Acne5
Can clog pores or trigger breakouts.
Glyceryl Stearate Se, Myristic Acid, Myristyl Myristate, Palmitic Acid, Stearic Acid
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Ceramide NP, Glyceryl Stearate Se, Myristic Acid, Myristyl Myristate, Palmitic Acid, Potassium Cetyl Phosphate, Stearic Acid
May Worsen Keratosis Pilaris5
May clog follicles or strip skin prone to keratosis pilaris.
Glyceryl Stearate Se, Myristic Acid, Myristyl Myristate, Palmitic Acid, Stearic Acid
Ingredients Side-by-side
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate (in both products)
Emulsion Stabilising
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Ammonium Polyacryloyldimethyl Taurate (in both products)
Emulsion Stabilising
Emollient
5 / 2
- Esters listed as pore-clogging in animal testing only
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Cleansing
2-3 / 0
- Fatty acids (stearic, oleic, lauric)
- Fatty alcohols (Malassezia)
- Possibly animal-derived
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Ceramide
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Barrier Repair
- Hydrating
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising, Viscosity Controlling
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-, monoammonium salt, homopolymer
Learn more about Ammonium Polyacryloyldimethyl Taurate →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →
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