SkinCeuticals
Antioxidant Resveratrol B E Nighttime SerumLa Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + NiacinamideA serum built around Niacinamide, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
Brand price
USD 175.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 60.99 · checked 25 Sept 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, Alcohol-free and Fungal-acne-safe; those rows are shaded. Tap any answer to see why.

Key Ingredients

Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.

Benefits

Hydrating5
Boosts hydration and relieves dry, tight skin.
Dimethicone, Glycerin, Propylene Glycol, Scutellaria Baicalensis Root Extract, Tocopherol
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Dimethicone, Glycerin, Niacinamide, Propylene Glycol, Resveratrol, Tocopherol
Reduces Irritation1
Eases discomfort and supports skin resilience.
Redness Reducing2
Soothes visible redness and calms irritation.
Hydrating7
Boosts hydration and relieves dry, tight skin.
Caprylic/Capric Triglyceride, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Dimethicone, Glycerin, Niacinamide, Octyldodecanol, Propylene Glycol, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Retinyl Palmitate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Irritation3
May cause stinging, redness or sensitivity.

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Cystoseira Tamariscifolia Extract
Skin Conditioning
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Propylene Glycol
Fragrance, Humectant, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Propylene Glycol is the aliphatic alcohol that conforms generally to the formula
Learn more about Propylene Glycol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →
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