SkinCeuticals Antioxidant Resveratrol B E Nighttime Serum vs La Roche-Posay Mela B3 Double Dose Discoloration Treatment with Melasyl™

SkinCeuticals

La Roche-Posay

A serum built around Niacinamide, for barrier repair and hydration.

A serum built around Niacinamide, for barrier repair and smoothing.

Serum

14 ingredients

34 ingredients

Brand price

USD 175.00 · checked 28 Sept 2026 · brand's site

Brand price

USD 54.99 · checked 25 Sept 2026 · brand's site

No retailer listed yet

Brand country not recorded

Brand from France

At a Glance

They come out differently on Fragrance-free, Fungal-acne-safe and Oil-free; those rows are shaded. Tap any answer to see why.

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Cetearyl Alcohol
Vitamin E1
Tocopherols — fat-soluble antioxidants.
Tocopherol
AHA1
Alpha hydroxy acids — water-soluble chemical exfoliants.
Citric Acid
Niacinamide1
Vitamin B3 — supports the barrier and evens tone.
Niacinamide

Hydrating5
Boosts hydration and relieves dry, tight skin.
Dimethicone, Glycerin, Propylene Glycol, Scutellaria Baicalensis Root Extract, Tocopherol
Barrier Repair6
Strengthens and restores the skin's natural barrier.
Dimethicone, Glycerin, Niacinamide, Propylene Glycol, Resveratrol, Tocopherol
Reduces Irritation1
Eases discomfort and supports skin resilience.
Scutellaria Baicalensis Root Extract
Redness Reducing2
Soothes visible redness and calms irritation.
Niacinamide, Scutellaria Baicalensis Root Extract

Hydrating5
Boosts hydration and relieves dry, tight skin.
Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Tocopherol
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Caprylyl Glycol, Cetearyl Alcohol, Dimethicone, Glycerin, Glycine Soja Oil, Neopentyl Glycol Dicaprate, Niacinamide, Octyldodecanol, Propylene Glycol, Sucrose Tristearate, Tocopherol
Reduces Irritation1
Eases discomfort and supports skin resilience.
Dipotassium Glycyrrhizate
Redness Reducing1
Soothes visible redness and calms irritation.
Niacinamide

May Trigger Acne1
Can clog pores or trigger breakouts.
Tocopherol
May Worsen Keratosis Pilaris1
May clog follicles or strip skin prone to keratosis pilaris.
Tocopherol
May Worsen Irritation2
May cause stinging, redness or sensitivity.
Alcohol Denat., Tocopherol
May Worsen Eczema1
May worsen itching or irritation for eczema-prone skin.
Alcohol Denat.

May Trigger Acne3
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glycine Soja Oil, Tocopherol
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Glycine Soja Oil, Hydrogenated Lecithin, Octyldodecanol, Sodium Stearoyl Glutamate, Sucrose Tristearate
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glycine Soja Oil, Tocopherol
May Worsen Oily Skin1
May increase shine or excess oil.
Glycine Soja Oil

Show highlights for:

Aqua (in both products)
Solvent
0 / —
Dimethicone (in both products)
Emollient
1 / 0
- Silicones
- Barrier Repair
- Hydrating
- Smoothing
Propylene Glycol (in both products)
Humectant
0 / 0
Dipropylene Glycol
Perfuming
0-1 / —
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Alcohol Denat. (in both products)
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Glycerin (in both products)
Humectant
0 / 0
- Possibly animal-derived
- Hydrating
Caffeine
Skin Conditioning
- Under-Eye Care
Sodium Chloride
Fragrance
0-1 / —
Peg/Ppg-18/18 Dimethicone
Emulsifying
0-1 / —
- Silicones

Aqua (in both products)
Solvent
0 / —
Neopentyl Glycol Dicaprate
Emollient
Alcohol Denat. (in both products)
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Dimethicone (in both products)
Emollient
1 / 0
- Silicones
- Barrier Repair
- Hydrating
- Smoothing
Hydroxypropyl Tetrahydropyrantriol
Skin Conditioning
Sucrose Tristearate
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Cetearyl Alcohol
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Glycerin (in both products)
Humectant
0 / 0
- Possibly animal-derived
- Hydrating
2-Mercaptonicotinoyl Glycine
Skin Conditioning

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Aqua
Solvent
Water
Learn more about Aqua →
Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →
Propylene Glycol
Fragrance, Humectant, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Propylene Glycol is the aliphatic alcohol that conforms generally to the formula
Learn more about Propylene Glycol →
Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →
Alcohol Denat.
Antifoaming, Antimicrobial, Astringent, Fragrance, Solvent, Viscosity Controlling
Alcohol Denat. is a drying alcohol.
Learn more about Alcohol Denat. →
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →
Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →