SkinCeuticals
Discoloration Defense Serum for Dark SpotsLa Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + NiacinamideA serum built around Niacinamide and Tranexamic acid, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
Brand price
USD 115.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 60.99 · checked 25 Sept 2026 · brand's site
At a Glance
They come out differently on Fragrance-free, Silicone-free, Fungal-acne-safe and Pore-clogger-free; those rows are shaded. Tap any answer to see why.
Key Ingredients
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Benefits
Hydrating4
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Glycerin, Hydroxyethyl Urea, Propylene Glycol
Barrier Repair5
Strengthens and restores the skin's natural barrier.
Allantoin, Caprylyl Glycol, Glycerin, Niacinamide, Propylene Glycol
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating7
Boosts hydration and relieves dry, tight skin.
Caprylic/Capric Triglyceride, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Dimethicone, Glycerin, Niacinamide, Octyldodecanol, Propylene Glycol, Tocopherol
Concerns
No concerns found
May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Retinyl Palmitate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Irritation3
May cause stinging, redness or sensitivity.
Ingredients Side-by-side
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Humectant
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Cystoseira Tamariscifolia Extract
Skin Conditioning
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Propylene Glycol
Fragrance, Humectant, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Propylene Glycol is the aliphatic alcohol that conforms generally to the formula
Learn more about Propylene Glycol →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →
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SkinCeuticals
Hyaluronic Acid Intensifier Multi-Glycan