SkinCeuticals
Advanced RGN-6A face cream built around Panthenol and Centella asiatica, for barrier repair and hydration.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 22.00 · checked 25 Sept 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site

At a Glance

They come out differently on Pore-clogger-free; that row is shaded. Tap any answer to see why.

Key Ingredients

Ceramide3
Skin-identical lipids that hold the barrier together.
Centella asiatica (Cica)4
Centella asiatica (cica), used to calm irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating18
Boosts hydration and relieves dry, tight skin.
Betaine, Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide AP, Ceramide EOP, Ceramide NP, Dimethiconol, Ectoin, Glutamic Acid, Glycerin, Glyceryl Glucoside, Hyaluronic Acid, Panthenol, Phenyl Trimethicone, Propanediol, Sodium Hyaluronate, Squalane, Tremella Fuciformis Extract
Barrier Repair21
Strengthens and restores the skin's natural barrier.
Allantoin, Behenyl Alcohol, Betaine, Bis-Diglyceryl Polyacyladipate-2, Caprylic/Capric Triglyceride, Centella Asiatica Extract, Ceramide AP, Ceramide EOP, Ceramide NP, Cetyl Ethylhexanoate, Dimethiconol, Glycerin, Glyceryl Caprylate, Glyceryl Stearate, Lecithin, Linolenic Acid, Octyldodecanol, Panthenol, Phenyl Trimethicone, Sphingolipids, Squalane
Reduces Irritation6
Eases discomfort and supports skin resilience.
Allantoin, Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid, Panthenol
Redness Reducing5
Soothes visible redness and calms irritation.
Allantoin, Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Madecassic Acid
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis23
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Behenyl Alcohol, Bis-Diglyceryl Polyacyladipate-2, C12-20 Alkyl Glucoside, C14-22 Alcohols, Ceramide AP, Ceramide EOP, Ceramide NP, Cetyl Ethylhexanoate, Ethylhexyl Olivate, Glyceryl Stearate, Hydrogenated Lecithin, Hydrogenated Rice Bran Oil, Lecithin, Linolenic Acid, Octyldodecanol, Phosphatidylcholine, Polyglyceryl-10 Laurate, Polyglyceryl-10 Stearate, Polyglyceryl-3 Methylglucose Distearate, Polyglyceryl-4 Oleate, Sodium Stearoyl Glutamate, Sphingolipids
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Skin Conditioning
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Ectoin
Skin Conditioning
4-Pyrimidinecarboxylic Acid, 1,4,5,6,-Tetrahydro-2-Methyl-, (4S)-
Learn more about Ectoin →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →
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