SkinCeuticals
Advanced RGN-6A face cream built around Ceramide and Hyaluronic acid, for barrier repair and hydration.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 27.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, EU-allergen-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating16
Boosts hydration and relieves dry, tight skin.
Beta-Glucan, Betaine, Butylene Glycol, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Ceramide AP, Ceramide NP, Fructooligosaccharides, Galactomyces Ferment Filtrate, Glycerin, Hydrolyzed Hyaluronic Acid, Saccharomyces Ferment Filtrate, Sodium Hyaluronate, Squalane, Stearic Acid, Tocopherol
Barrier Repair21
Strengthens and restores the skin's natural barrier.
Allantoin, Betaine, Bifida Ferment Lysate, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Caprylyl Glycol, Centella Asiatica Extract, Ceramide AP, Ceramide NP, Cetearyl Alcohol, Cholesterol, Cyclohexasiloxane, Dicaprylyl Ether, Glycerin, Glyceryl Stearate, Laminaria Japonica Extract, Mangifera Indica Seed Butter, Sodium Polyacrylate, Squalane, Stearic Acid, Tocopherol
Reduces Irritation3
Eases discomfort and supports skin resilience.
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis13
May feed the yeast involved in seborrheic dermatitis.
Butyrospermum Parkii Butter, Ceramide AP, Ceramide NP, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Glycosphingolipids, Hydrogenated Lecithin, Mangifera Indica Seed Butter, Pentaerythrityl Distearate, Sodium Stearoyl Glutamate, Stearic Acid, Tetraacetylphytosphingosine
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Oily Skin3
May increase shine or excess oil.
Butyrospermum Parkii Butter, Mangifera Indica Seed Butter, Squalane
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Skin Conditioning
Emulsifying
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Adenosine
Skin Conditioning
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Learn more about Adenosine →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →
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