SkinCeuticals
Advanced RGN-6A face cream built around Panthenol and Centella asiatica, for barrier repair and hydration.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 17.99 · checked 26 Sept 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site

At a Glance

They come out differently on Oil-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol2
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating11
Boosts hydration and relieves dry, tight skin.
Betaine, Butylene Glycol, Ceramide NP, Erythritol, Glycerin, Panthenol, Propanediol, Squalane, Stearyl Alcohol, Tocopherol, Xylitol
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Behenyl Alcohol, Betaine, Centella Asiatica Extract, Ceramide NP, Cetearyl Alcohol, Cetyl Ethylhexanoate, Cholesterol, Glycerin, Glyceryl Stearate, Panthenol, Propylheptyl Caprylate, Squalane, Stearyl Alcohol, Sucrose Distearate, Tocopherol, Xylitol
Reduces Irritation8
Eases discomfort and supports skin resilience.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Madecassic Acid, Madecassoside, Panthenol
Redness Reducing7
Soothes visible redness and calms irritation.
Asiatic Acid, Asiaticoside, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Madecassic Acid, Madecassoside
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol

Concerns

May Trigger Acne5
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glyceryl Stearate Se, Sorbitan Isostearate, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis12
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Behenyl Alcohol, Ceramide NP, Cetearyl Alcohol, Cetyl Ethylhexanoate, Glyceryl Stearate, Glyceryl Stearate Se, Hydrogenated Lecithin, Polyglyceryl-2 Stearate, Sorbitan Isostearate, Stearyl Alcohol, Sucrose Distearate
May Worsen Keratosis Pilaris5
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glyceryl Stearate Se, Sorbitan Isostearate, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Skin Conditioning
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →
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