Cetaphil Moisturizing Cream vs SkinCeuticals Advanced RGN-6

Cetaphil

SkinCeuticals

A face cream built around Panthenol and Niacinamide, for barrier repair and smoothing.

A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.

Face cream

23 ingredients

29 ingredients

Brand price

Not recorded · brand's site

Brand price

USD 195.00 · checked 28 Sept 2026 · brand's site

No retailer listed yet

Brand from United States

Brand country not recorded

At a Glance

They come out differently on EU-allergen-free and Pore-clogger-free; those rows are shaded. Tap any answer to see why.

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Cetyl Alcohol
Vitamin E1
Tocopherols — fat-soluble antioxidants.
Tocopheryl Acetate
Panthenol (provitamin B5)1
Provitamin B5 — a humectant and soother.
Panthenol
AHA1
Alpha hydroxy acids — water-soluble chemical exfoliants.
Citric Acid

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Cetyl Alcohol
Face oil1
An oil formulated to be used on the face.
Squalane
Vitamin E1
Tocopherols — fat-soluble antioxidants.
Tocopherol
AHA1
Alpha hydroxy acids — water-soluble chemical exfoliants.
Citric Acid

Hydrating8
Boosts hydration and relieves dry, tight skin.
Dimethicone, Dimethiconol, Glycerin, Helianthus Annuus Seed Oil, Panthenol, Pantolactone, Petrolatum, Propylene Glycol
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Cetyl Alcohol, Dicaprylyl Ether, Dimethicone, Dimethiconol, Glycerin, Glyceryl Stearate, Helianthus Annuus Seed Oil, Niacinamide, Panthenol, Petrolatum, Propylene Glycol
Reduces Irritation1
Eases discomfort and supports skin resilience.
Panthenol
Redness Reducing1
Soothes visible redness and calms irritation.
Niacinamide

May Trigger Acne2
Can clog pores or trigger breakouts.
Cetyl Alcohol, Prunus Amygdalus Dulcis Oil
May Worsen Seborrheic Dermatitis6
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetyl Alcohol, Glyceryl Stearate, Helianthus Annuus Seed Oil, PEG-30 Stearate, Prunus Amygdalus Dulcis Oil
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
Cetyl Alcohol, Prunus Amygdalus Dulcis Oil
May Worsen Oily Skin3
May increase shine or excess oil.
Helianthus Annuus Seed Oil, Petrolatum, Prunus Amygdalus Dulcis Oil

May Trigger Acne3
Can clog pores or trigger breakouts.
Cetyl Alcohol, Palmitic Acid, Tocopherol
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Cetyl Alcohol, Palmitic Acid, Tocopherol
May Worsen Oily Skin2
May increase shine or excess oil.
Butyrospermum Parkii Butter, Squalane

Show highlights for:

Water
Skin Conditioning
Glycerin (in both products)
Humectant
0 / 0
- Possibly animal-derived
- Hydrating
Petrolatum
Emollient
0 / —
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
Dicaprylyl Ether
Emollient
Dimethicone (in both products)
Emollient
1 / 0
- Silicones
- Barrier Repair
- Hydrating
- Smoothing
Glyceryl Stearate
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Cetyl Alcohol (in both products)
Emollient
2 / 2
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Helianthus Annuus Seed Oil
Emollient
0 / 0
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
PEG-30 Stearate
Cleansing
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Panthenol
Skin Conditioning
0 / 0
- Panthenol (provitamin B5)
- Barrier Repair
- Hydrating
- Reduces Irritation

Aqua
Solvent
0 / —
Glycerin (in both products)
Humectant
0 / 0
- Possibly animal-derived
- Hydrating
Ethyl Oleate
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Squalane
Emollient
1 / 0
- Face oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
C12-16 Alcohols
Emollient
- Fatty alcohols (Malassezia)
- May Worsen Seborrheic Dermatitis
Glyceryl Stearate Citrate
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Maltodextrin
Skin Conditioning
0-1 / —
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →
Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →
Cetyl Alcohol
Emulsion Stabilising, Fragrance, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetyl Alcohol isn't fungal acne safe.
Learn more about Cetyl Alcohol →
Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →
Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →
Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →
Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →