SkinCeuticals
Advanced RGN-6A face cream built around Vitamin E and Panthenol, for barrier repair and hydration.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 27.00 · checked 25 Sept 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
At a Glance
They come out differently on Cruelty-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating15
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Dimethicone, Glycerin, Helianthus Annuus Seed Oil, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Panthenol, Propanediol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Stearic Acid, Tocopherol, Trehalose
Barrier Repair17
Strengthens and restores the skin's natural barrier.
Allantoin, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Dimethicone, Elaeis Guineensis Oil, Glycerin, Glyceryl Caprylate, Glyceryl Stearate, Glycine Soja Oil, Helianthus Annuus Seed Oil, Limnanthes Alba Seed Oil, Oryza Sativa Bran Wax, Palmitic Acid, Panthenol, Stearic Acid, Tocopherol
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne8
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glycine Soja Oil, Lauric Acid, Myristic Acid, Palmitic Acid, Sorbitan Isostearate, Stearic Acid, Tocopherol
May Worsen Seborrheic Dermatitis17
May feed the yeast involved in seborrheic dermatitis.
Butyrospermum Parkii Butter, Cetearyl Alcohol, Elaeis Guineensis Oil, Glyceryl Stearate, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydrogenated Lecithin, Lauric Acid, Limnanthes Alba Seed Oil, Myristic Acid, Oryza Sativa Bran Wax, Palmitic Acid, Polyglyceryl-10 Stearate, Polyglyceryl-3 Methylglucose Distearate, Sodium Acetylated Hyaluronate, Sorbitan Isostearate, Stearic Acid
May Worsen Keratosis Pilaris8
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glycine Soja Oil, Lauric Acid, Myristic Acid, Palmitic Acid, Sorbitan Isostearate, Stearic Acid, Tocopherol
May Worsen Oily Skin5
May increase shine or excess oil.
Butyrospermum Parkii Butter, Elaeis Guineensis Oil, Glycine Soja Oil, Helianthus Annuus Seed Oil, Limnanthes Alba Seed Oil
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Skin Conditioning
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Emollient
3 / 0
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Adenosine
Skin Conditioning
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Learn more about Adenosine →
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