SkinCeuticals
Advanced RGN-6A face cream built around Panthenol and Vitamin E, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
Not recorded · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
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At a Glance

They come out differently on Fragrance-free, Alcohol-free and Silicone-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Glycerin, Panthenol, Pantolactone, Squalane, Tocopherol
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, Cetearyl Alcohol, Cetearyl Isononanoate, Glycerin, Glyceryl Stearate Citrate, Hydrogenated Coco-Glycerides, Isopropyl Palmitate, Panthenol, Squalane, Tocopherol
Smoothing7
Refines rough or uneven texture.
Cetearyl Alcohol, Cetearyl Isononanoate, Citric Acid, Glyceryl Stearate Citrate, Hydrogenated Coco-Glycerides, Isopropyl Palmitate, Squalane
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol

Concerns

May Trigger Acne3
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Butyrospermum Parkii Butter, Cetearyl Alcohol, Cetearyl Isononanoate, Glyceryl Stearate Citrate, Hydrogenated Coco-Glycerides, Isopropyl Palmitate, Lauroyl Lysine
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Skin Conditioning
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
4 / 1
- Esters listed as pore-clogging in animal testing only
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Glyceryl Stearate Citrate (in both products)
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Glyceryl Stearate Citrate (in both products)
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Glyceryl Stearate Citrate
Skin Conditioning, Emollient, Emulsifying
Glyceryl Stearate Citrate isn't fungal acne safe.
Learn more about Glyceryl Stearate Citrate →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →
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