SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Alpha arbutin, for barrier repair and antioxidant protection.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
Not recorded · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
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At a Glance

They come out differently on Fragrance-free and EU-allergen-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating10
Boosts hydration and relieves dry, tight skin.
Betaine, Butylene Glycol, Caprylic/Capric Triglyceride, Dimethiconol, Glycerin, Helianthus Annuus Seed Oil, Phenyl Trimethicone, Propanediol, Tocopherol, Tripropylene Glycol
Barrier Repair15
Strengthens and restores the skin's natural barrier.
Betaine, Canola Oil, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Daucus Carota Sativa Seed Oil, Dimethiconol, Glycerin, Helianthus Annuus Seed Oil, Isononyl Isononanoate, Macadamia Integrifolia Seed Oil, Niacinamide, Olea Europaea Fruit Oil, Pentaerythrityl Tetraethylhexanoate, Phenyl Trimethicone, Tocopherol
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol

Concerns

May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Lauric Acid, Olea Europaea Fruit Oil, Tocopherol
May Worsen Seborrheic Dermatitis12
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Canola Oil, Castor Oil/Ipdi Copolymer, Cetearyl Alcohol, Cetearyl Glucoside, Daucus Carota Sativa Seed Oil, Helianthus Annuus Seed Oil, Lauric Acid, Macadamia Integrifolia Seed Oil, Olea Europaea Fruit Oil, Polyglyceryl-10 Laurate, Sodium Laurate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Lauric Acid, Olea Europaea Fruit Oil, Tocopherol
May Worsen Oily Skin5
May increase shine or excess oil.
Canola Oil, Daucus Carota Sativa Seed Oil, Helianthus Annuus Seed Oil, Macadamia Integrifolia Seed Oil, Olea Europaea Fruit Oil
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
Skin Conditioning
Pentaerythrityl Tetraethylhexanoate
Emollient
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Adenosine
Skin Conditioning
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Learn more about Adenosine →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →
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