SkinCeuticals
Advanced RGN-6A face cream built around Vitamin E, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
Not recorded · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
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At a Glance
Every check both products could be assessed on comes out the same. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating8
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Ceramide NP, Dimethicone, Glucose, Glycerin, Mannitol, Stearic Acid, Tocopherol
Barrier Repair18
Strengthens and restores the skin's natural barrier.
Arachidyl Alcohol, Behenyl Alcohol, Canola Oil, Ceramide NP, Cetyl Ethylhexanoate, Cholesterol, Dimethicone, Glycerin, Glyceryl Caprylate, Glycine Max Oil, Hydrogenated Poly(C6-14 Olefin), Hydroxypropyl Bispalmitamide MEA, Palmitic Acid, Panax Ginseng Root Water, Pentaerythrityl Tetraisostearate, Phytosphingosine, Stearic Acid, Tocopherol
Smoothing12
Refines rough or uneven texture.
Arachidyl Alcohol, Behenyl Alcohol, Canola Oil, Cetyl Ethylhexanoate, Cholesterol, Dimethicone, Glyceryl Caprylate, Glycine Max Oil, Hydrogenated Poly(C6-14 Olefin), Hydroxypropyl Bispalmitamide MEA, Palmitic Acid, Pentaerythrityl Tetraisostearate
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne7
Can clog pores or trigger breakouts.
Arachidic Acid, Myristic Acid, Palmitic Acid, Pentaerythrityl Tetraisostearate, Sorbitan Isostearate, Stearic Acid, Tocopherol
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Arachidic Acid, Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, C12-20 Alkyl Glucoside, C14-22 Alcohols, Canola Oil, Ceramide NP, Cetyl Ethylhexanoate, Glycine Max Oil, Hydrogenated Lecithin, Hydroxypropyl Bispalmitamide MEA, Myristic Acid, Palmitic Acid, Pentaerythrityl Tetraisostearate, Phytosphingosine, Polysorbate 20, Sorbitan Isostearate, Stearic Acid
May Worsen Keratosis Pilaris7
May clog follicles or strip skin prone to keratosis pilaris.
Arachidic Acid, Myristic Acid, Palmitic Acid, Pentaerythrityl Tetraisostearate, Sorbitan Isostearate, Stearic Acid, Tocopherol
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Skin Conditioning
Pentaerythrityl Tetraisostearate
Emollient
2 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Hydrogenated Poly(C6-14 Olefin)
Emollient
Cleansing
2-3 / 0
- Fatty acids (stearic, oleic, lauric)
- Fatty alcohols (Malassezia)
- Possibly animal-derived
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Palmitic Acid (in both products)
Emollient
2 / 0
- Fatty acids (stearic, oleic, lauric)
- Possibly animal-derived
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →
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