SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Ceramide, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
Not recorded · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
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At a Glance
They come out differently on Cruelty-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol3
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating13
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Jojoba Esters, Mannitol, Panthenol, Polyglycerin-3, Sodium Hyaluronate, Stearyl Alcohol, Tocopherol
Barrier Repair22
Strengthens and restores the skin's natural barrier.
Behenyl Alcohol, C10-18 Triglycerides, Caprylic/Capric Triglyceride, Ceramide NP, Cetearyl Alcohol, Cetyl Alcohol, Dicaprylyl Ether, Glycerin, Glyceryl Stearate, Glyceryl Stearates, Helianthus Annuus Seed Wax, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polydecene, Jojoba Esters, Niacinamide, Oryza Sativa Bran Oil, Panthenol, Pentaerythrityl Tetraethylhexanoate, Phytosphingosine, Stearyl Alcohol, Tocopherol, Zea Mays Starch
Reduces Irritation3
Eases discomfort and supports skin resilience.
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne5
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Cetyl Alcohol, Sorbitan Isostearate, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis17
May feed the yeast involved in seborrheic dermatitis.
Behenyl Alcohol, C10-18 Triglycerides, Ceramide NP, Cetearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate, Glyceryl Stearates, Helianthus Annuus Seed Wax, Hydrogenated Lecithin, Jojoba Esters, Oryza Sativa Bran Oil, Phytosphingosine, Polyglyceryl-10 Laurate, Polyglyceryl-6 Distearate, Sodium Stearoyl Glutamate, Sorbitan Isostearate, Stearyl Alcohol
May Worsen Keratosis Pilaris5
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Cetyl Alcohol, Sorbitan Isostearate, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Perfuming
Emollient
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Pentaerythrityl Tetraethylhexanoate
Emollient
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Cetyl Alcohol
Emulsion Stabilising, Fragrance, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetyl Alcohol isn't fungal acne safe.
Learn more about Cetyl Alcohol →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →
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