SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Panthenol, for barrier repair and hydration.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
Not recorded · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
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At a Glance
They come out differently on Cruelty-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating15
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Ceramide NP, Glycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Inositol, Panthenol, Propanediol, Simmondsia Chinensis Seed Oil, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Tocopherol
Barrier Repair19
Strengthens and restores the skin's natural barrier.
Ascorbyl Tetraisopalmitate, Behenyl Alcohol, Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylic/Capric Triglyceride, Centella Asiatica Extract, Ceramide NP, Cetearyl Alcohol, Diisostearyl Malate, Eriobotrya Japonica Leaf Extract, Glycerin, Isononyl Isononanoate, Niacinamide, Oryza Sativa Bran Oil, Palmitic Acid, Panthenol, Phytosphingosine, Simmondsia Chinensis Seed Oil, Tocopherol
Reduces Irritation2
Eases discomfort and supports skin resilience.
Redness Reducing2
Soothes visible redness and calms irritation.
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Palmitic Acid, Simmondsia Chinensis Seed Oil, Tocopherol
May Worsen Seborrheic Dermatitis18
May feed the yeast involved in seborrheic dermatitis.
Ascorbyl Tetraisopalmitate, Behenyl Alcohol, Butyrospermum Parkii Butter, C12-16 Alcohols, Castor Oil/Ipdi Copolymer, Ceramide NP, Cetearyl Alcohol, Diisostearyl Malate, Haematococcus Pluvialis Oil, Hydrogenated Lecithin, Oryza Sativa Bran Oil, Palmitic Acid, Phytosphingosine, Polyglyceryl-3 Methylglucose Distearate, Simmondsia Chinensis Seed Oil, Sodium Acetylated Hyaluronate, Sorbitan Stearate, Sucrose Cocoate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Palmitic Acid, Simmondsia Chinensis Seed Oil, Tocopherol
May Worsen Oily Skin4
May increase shine or excess oil.
Butyrospermum Parkii Butter, Haematococcus Pluvialis Oil, Oryza Sativa Bran Oil, Simmondsia Chinensis Seed Oil
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
0-2 / 0
- Face oil
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Emulsifying
0 / 1
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
C12-16 Alcohols (in both products)
Emollient
- Fatty alcohols (Malassezia)
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →C12-16 Alcohols
Antistatic, Emulsion Stabilising, Hair Conditioning, Emollient, Viscosity Controlling
C12-16 Alcohols isn't fungal acne safe.
Learn more about C12-16 Alcohols →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Hydrogenated Lecithin
Skin Conditioning, Emulsifying
Hydrogenated Lecithin isn't fungal acne safe.
Learn more about Hydrogenated Lecithin →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Adenosine
Skin Conditioning
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Learn more about Adenosine →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →
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