La Roche-Posay
Hyalu B5 Suractivated Cream with Hyaluornic AcidSkinCeuticals
Advanced RGN-6A face cream built around Panthenol and Hyaluronic acid, for hydration and barrier repair.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 39.99 · checked 25 Sept 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, Alcohol-free and Oil-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol2
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating11
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Butylene Glycol, Caprylic/Capric Triglyceride, Dimethicone, Ectoin, Glycerin, Hydrolyzed Hyaluronic Acid, Panthenol, Propanediol, Sodium Hyaluronate, Stearic Acid
Barrier Repair12
Strengthens and restores the skin's natural barrier.
Behenyl Alcohol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetyl Alcohol, Dimethicone, Glycerin, Isohexadecane, Isopropyl Isostearate, Octyldodecanol, Palmitic Acid, Panthenol, Stearic Acid
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol

Concerns

May Trigger Acne6
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Cetyl Alcohol, Isopropyl Isostearate, Myristic Acid, Palmitic Acid, Stearic Acid
May Worsen Seborrheic Dermatitis14
May feed the yeast involved in seborrheic dermatitis.
Acetyl Glucosamine, Behenyl Alcohol, C13-14 Isoalkane, Cetearyl Alcohol, Cetearyl Glucoside, Cetyl Alcohol, Disodium Stearoyl Glutamate, Isopropyl Isostearate, Laureth-7, Myristic Acid, Octyldodecanol, Palmitic Acid, PEG-100 Stearate, Stearic Acid
May Worsen Keratosis Pilaris6
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Cetyl Alcohol, Isopropyl Isostearate, Myristic Acid, Palmitic Acid, Stearic Acid
May Worsen Irritation3
May cause stinging, redness or sensitivity.
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Emollient
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
Emollient
5 / 0
- Esters listed as pore-clogging in animal testing only
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate (in both products)
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Cetyl Alcohol
Emulsion Stabilising, Fragrance, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetyl Alcohol isn't fungal acne safe.
Learn more about Cetyl Alcohol →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Adenosine
Skin Conditioning
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Learn more about Adenosine →Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising, Viscosity Controlling
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-, monoammonium salt, homopolymer
Learn more about Ammonium Polyacryloyldimethyl Taurate →Ectoin
Skin Conditioning
4-Pyrimidinecarboxylic Acid, 1,4,5,6,-Tetrahydro-2-Methyl-, (4S)-
Learn more about Ectoin →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →
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