SkinCeuticals
Advanced RGN-6A face cream built around Panthenol, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 56.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
At a Glance
They come out differently on Fragrance-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating9
Boosts hydration and relieves dry, tight skin.
Beta-Glucan, Butylene Glycol, Ceramide NP, Dimethicone, Glycerin, Panthenol, Propanediol, Squalane, Tocopherol
Barrier Repair14
Strengthens and restores the skin's natural barrier.
Ceramide NP, Cetearyl Alcohol, Copernicia Cerifera Wax, Dimethicone, Glycerin, Glyceryl Caprylate, Glyceryl Stearate, Glyceryl Stearate Citrate, Glycine Soja Oil, Limnanthes Alba Seed Oil, Panthenol, Pentaerythrityl Tetraethylhexanoate, Squalane, Tocopherol
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne4
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Glycine Soja Oil, Sorbitan Isostearate, Tocopherol
May Worsen Seborrheic Dermatitis12
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ceramide NP, Cetearyl Alcohol, Copernicia Cerifera Wax, Glyceryl Stearate, Glyceryl Stearate Citrate, Glycine Soja Oil, Limnanthes Alba Seed Oil, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Polyglyceryl-10 Stearate, Sorbitan Isostearate
May Worsen Keratosis Pilaris4
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Glycine Soja Oil, Sorbitan Isostearate, Tocopherol
May Worsen Oily Skin3
May increase shine or excess oil.
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Skin Conditioning
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Skin Conditioning
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Glyceryl Stearate Citrate (in both products)
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Glyceryl Stearate Citrate (in both products)
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Glyceryl Stearate Citrate
Skin Conditioning, Emollient, Emulsifying
Glyceryl Stearate Citrate isn't fungal acne safe.
Learn more about Glyceryl Stearate Citrate →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Adenosine
Skin Conditioning
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Learn more about Adenosine →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →
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