Medicube
Azelaic Acid 16 Calming SerumA serum built around Niacinamide and Hyaluronic acid, for hydration and barrier repair.
A serum built around Azelaic acid and Niacinamide, for barrier repair and smoothing.
Brand price
USD 26.00 · checked 26 Sept 2026 · brand's site
Brand price
USD 26.00 · checked 26 Sept 2026 · brand's site
At a Glance
They come out differently on Fragrance-free, Alcohol-free and Vegan; those rows are shaded. Tap any answer to see why.
Key Ingredients
Hyaluronic acid3
Hyaluronic acid and its salts; a humectant that binds water to the skin.
Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer
Centella asiatica (Cica)1
Centella asiatica (cica), used to calm irritation.
Benefits
Hydrating16
Boosts hydration and relieves dry, tight skin.
Acetyl Hexapeptide-8, Butylene Glycol, Glucose, Glycerin, Glyceryl Glucoside, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Panthenol, Propanediol, Simmondsia Chinensis Seed Oil, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sorbitol, Squalane, Trehalose
Barrier Repair11
Strengthens and restores the skin's natural barrier.
Acetyl Tetrapeptide-3, Allantoin, Aloe Barbadensis Flower Extract, Citrus Aurantium Bergamia Fruit Oil, Glycerin, Neopentyl Glycol Dicaprate, Niacinamide, Panthenol, Simmondsia Chinensis Seed Oil, Squalane, Tripeptide-1
Reduces Irritation3
Eases discomfort and supports skin resilience.
Hydrating7
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Ceramide NP, Panthenol, Propanediol, Propylene Glycol, Squalane
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Allantoin, Aloe Barbadensis Flower Extract, Butyrospermum Parkii Butter, Centella Asiatica Extract, Ceramide NP, Glyceryl Caprylate, Hydrolyzed Pea Protein, Lecithin, Niacinamide, Olea Europaea Fruit Oil, Panthenol, Propylene Glycol, Squalane
Reduces Irritation3
Eases discomfort and supports skin resilience.
Redness Reducing4
Soothes visible redness and calms irritation.
Allantoin, Azelaic Acid, Centella Asiatica Extract, Niacinamide
Concerns
May Worsen Seborrheic Dermatitis7
May feed the yeast involved in seborrheic dermatitis.
Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Simmondsia Chinensis Seed Oil, Sodium Acetylated Hyaluronate
May Worsen Keratosis Pilaris1
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Seborrheic Dermatitis4
May feed the yeast involved in seborrheic dermatitis.
Butyrospermum Parkii Butter, Ceramide NP, Lecithin, Olea Europaea Fruit Oil
May Worsen Keratosis Pilaris1
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Oily Skin3
May increase shine or excess oil.
Butyrospermum Parkii Butter, Olea Europaea Fruit Oil, Squalane
Ingredients Side-by-side
Water (in both products)
Skin Conditioning
Emollient
1,2-Hexanediol (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Humectant
Water (in both products)
Skin Conditioning
Fragrance
0 / —
- Denatured alcohol
- May Worsen Dryness
- May Worsen Eczema
- May Worsen Irritation
- May Worsen Rosacea
1,2-Hexanediol (in both products)
Skin Conditioning
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water
Antiplaque, Skin Conditioning, Solvent
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Learn more about Water →Propanediol
Solvent, Viscosity Controlling
Propanediol is the organic compound that conforms to the formula
Learn more about Propanediol →1,2-Hexanediol
Skin Conditioning, Solvent
We don't have a description for 1,2-Hexanediol yet.
Learn more about 1,2-Hexanediol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Panthenol
Antistatic, Hair Conditioning, Skin Conditioning
Panthenol is panthenol (provitamin B5).
Learn more about Panthenol →Allantoin
Skin Conditioning, Skin Protecting, Soothing
Urea, (2,5-dioxo-4-imidazolidinyl)-
Learn more about Allantoin →Melia Azadirachta Leaf Extract
Skin Conditioning
Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae
Learn more about Melia Azadirachta Leaf Extract →Melia Azadirachta Flower Extract
Skin Conditioning
Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae
Learn more about Melia Azadirachta Flower Extract →Butylene Glycol
Fragrance, Humectant, Skin Conditioning, Solvent, Viscosity Controlling
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Learn more about Butylene Glycol →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →
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