Medik8
Niacinamide PeptidesLa Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + NiacinamideA serum built around Niacinamide and Zinc salt, for barrier repair and hydration.
A serum built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
Brand price
GBP 49.00 · checked 8 Oct 2026 · brand's site
Brand price
USD 60.99 · checked 25 Sept 2026 · brand's site

At a Glance

They come out differently on Fragrance-free, Oil-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Hyaluronic acid1
Hyaluronic acid and its salts; a humectant that binds water to the skin.

Benefits

Hydrating8
Boosts hydration and relieves dry, tight skin.
Acetyl Glucosamine, Caprylic/Capric Triglyceride, Crambe Abyssinica Seed Oil, Dimethicone, Glycerin, Sodium Hyaluronate, Tocopherol, Zinc PCA
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Behenyl Alcohol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetyl Palmitate, Crambe Abyssinica Seed Oil, Dimethicone, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Tocopherol
Hydrating7
Boosts hydration and relieves dry, tight skin.
Caprylic/Capric Triglyceride, Dimethicone, Dipotassium Glycyrrhizate, Glycerin, Propylene Glycol, Sodium Hyaluronate, Tocopherol
Barrier Repair9
Strengthens and restores the skin's natural barrier.
Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Dimethicone, Glycerin, Niacinamide, Octyldodecanol, Propylene Glycol, Tocopherol

Concerns

May Trigger Acne3
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis13
May feed the yeast involved in seborrheic dermatitis.
Acetyl Glucosamine, Behenyl Alcohol, Cetearyl Alcohol, Cetyl Palmitate, Crambe Abyssinica Seed Oil, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitoyl Tetrapeptide-10, Polyglyceryl-3 Stearate, Polysorbate 60, Polysorbate 80, Sorbitan Isostearate, Sorbitan Stearate
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Seborrheic Dermatitis3
May feed the yeast involved in seborrheic dermatitis.
Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Retinyl Palmitate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Irritation3
May cause stinging, redness or sensitivity.

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Skin Conditioning
- Fatty alcohols (Malassezia)
- Dark Spots
- Hydrating
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Cystoseira Tamariscifolia Extract
Skin Conditioning
Skin Conditioning
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Caprylic/Capric Triglyceride
Fragrance, Perfuming, Occlusive, Solvent
Caprylic/Capric Triglyceride is the mixed triester of glycerin and caprylic and capric acids.
Learn more about Caprylic/Capric Triglyceride →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Sodium Hyaluronate
Humectant, Skin Conditioning
Sodium Hyaluronate is a hyaluronic acid.
Learn more about Sodium Hyaluronate →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Carnosine
Skin Conditioning
L-histidine, N-beta-alanyl
Learn more about Carnosine →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →
Similar Comparisons
Each product against its closest dupes.
- View the comparison

Medik8
Niacinamide Peptides

Neutrogena
Collagen Bank Laser Perfecting Face Serum
- View the comparison

La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide

La Roche-Posay
Mela B3 Double Dose Discoloration Treatment with Melasyl™
- View the comparison

Medik8
Niacinamide Peptides

COSRX
The Alpha-Arbutin 2 Discoloration Care Serum
- View the comparison

La Roche-Posay
Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide

SkinCeuticals
Hyaluronic Acid Intensifier Multi-Glycan