SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Hyaluronic acid, for barrier repair and hydration.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 99.00 · checked 8 Oct 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
At a Glance
They come out differently on Fragrance-free, EU-allergen-free, Silicone-free and Cruelty-free; those rows are shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating13
Boosts hydration and relieves dry, tight skin.
Betaine, Glycerin, Hyaluronic Acid, Inositol, Jojoba Esters, Mannitol, Propanediol, Squalane, Stearic Acid, Tocopherol, Trehalose, Urea, Yeast Amino Acids
Barrier Repair15
Strengthens and restores the skin's natural barrier.
Betaine, Bis-Diglyceryl Polyacyladipate-2, Caprylic/Capric/Myristic/Stearic Triglyceride, Cetyl Alcohol, Cocos Nucifera Oil, Glycerin, Glyceryl Stearate, Isononyl Isononanoate, Jojoba Esters, Mangifera Indica Seed Butter, Niacinamide, Palmitic Acid, Squalane, Stearic Acid, Tocopherol
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne8
Can clog pores or trigger breakouts.
Arachidic Acid, Cetyl Alcohol, Cocos Nucifera Oil, Lauric Acid, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol
May Worsen Seborrheic Dermatitis16
May feed the yeast involved in seborrheic dermatitis.
Arachidic Acid, Bis-Diglyceryl Polyacyladipate-2, Caprylic/Capric/Myristic/Stearic Triglyceride, Cetyl Alcohol, Cetyl Phosphate, Cocos Nucifera Oil, Glyceryl Stearate, Hydrolyzed Jojoba Esters, Jojoba Esters, Lauric Acid, Mangifera Indica Seed Butter, Myristic Acid, Palmitic Acid, PEG-100 Stearate, Phosphatidylcholine, Stearic Acid
May Worsen Keratosis Pilaris8
May clog follicles or strip skin prone to keratosis pilaris.
Arachidic Acid, Cetyl Alcohol, Cocos Nucifera Oil, Lauric Acid, Myristic Acid, Palmitic Acid, Stearic Acid, Tocopherol
May Worsen Oily Skin3
May increase shine or excess oil.
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Skin Conditioning
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Cetyl Alcohol (in both products)
Emollient
2 / 2
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Caprylic/Capric/Myristic/Stearic Triglyceride
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Cetyl Alcohol
Emulsion Stabilising, Fragrance, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetyl Alcohol isn't fungal acne safe.
Learn more about Cetyl Alcohol →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Maltodextrin
Absorbent, Binding, Emulsion Stabilising, Film Forming, Hair Conditioning, Skin Conditioning
Maltodextrin
Learn more about Maltodextrin →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →
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